肥胖症和 2 型糖尿病患者减肥手术的成本效益

IF 3.6 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM Journal of Diabetes Research Pub Date : 2023-12-16 DOI:10.1155/2023/9686729
Gábor Kovács, Elemér Mohos, János Tibor Kis, Ádám Tabák, Péter Gerendy, Judit Pettkó, Dávid Nagy, Dávid Győrbíró, Zoltán Kaló
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引用次数: 0

摘要

目的。多项研究表明,减肥手术对减轻体重和控制血糖有积极作用。此外,减肥手术的成本效益也在多项分析中得到证实。本次分析的目的是根据已公布的临床试验结果建立经济模型,与传统的糖尿病治疗方法相比,证明匈牙利 2 型糖尿病肥胖患者接受减肥手术的成本效益。材料与方法。进入模拟模型的患者年龄为 45 岁,体重为 kg/m2,患有 2 型糖尿病。该模型从公共支付方的角度出发,对袖状胃切除术(SG)和Roux-en-Y 胃旁路术(RYGB)与传统糖尿病治疗方法进行了比较。分别提供了三个 BMI 类别的结果。结果。基础案例分析表明,两种手术类型均占主导地位,即在三个体重指数类别中,它们分别节省了 17 064 至 24 384 欧元的公共支付支出,并改善了健康状况(质量调整生命年收益(QALY)为 1.36 至 1.50)。减肥手术延长了预期寿命和所有受调查糖尿病并发症的无病生存时间。所有情景分析都证实了基础案例分析的稳健性,与传统的糖尿病治疗方法相比,减肥手术仍占主导地位。结论这项成本效益分析的结果凸显了减肥手术作为传统糖尿病治疗方法替代品在肥胖人群中的重要性。因此,强烈建议在匈牙利让更多的人接受这些手术。
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Cost-Effectiveness of Bariatric Surgery in Patients Living with Obesity and Type 2 Diabetes
Aims. The favourable effects of bariatric surgeries on body weight reduction and glucose control have been demonstrated in several studies. Additionally, the cost-effectiveness of bariatric surgeries has been confirmed in several analyses. The aim of the current analysis was to demonstrate the cost-effectiveness of bariatric surgeries in obese patients with type 2 diabetes in Hungary compared to conventional diabetes treatments based on economic modelling of published clinical trial results. Materials and Methods. Patients entered the simulation model at the age of 45 with  kg/m2 and type 2 diabetes. The model was performed from the public payer’s perspective, comparing sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) procedures to conventional care of diabetes. The results were provided separately for three BMI categories. Results. The base-case analysis demonstrated that both surgery types were dominant; i.e., they saved 17 064 to 24 384 Euro public payer expenditures and resulted in improved health outcomes (1.36 to 1.50 quality-adjusted life years gain (QALY)) in the three BMI categories. Bariatric surgeries extended the life expectancy and the disease-free survival times of all the investigated diabetes complications. All the scenario analyses confirmed the robustness of the base-case analysis, such that bariatric surgeries remained dominant compared to conventional diabetes treatments. Conclusion. The results of this cost-effectiveness analysis highlight the importance of bariatric surgeries as alternatives to conventional diabetes treatments in the obese population. Therefore, it is strongly recommended that a wider population has access to these surgeries in Hungary.
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来源期刊
Journal of Diabetes Research
Journal of Diabetes Research ENDOCRINOLOGY & METABOLISM-MEDICINE, RESEARCH & EXPERIMENTAL
CiteScore
8.40
自引率
2.30%
发文量
152
审稿时长
14 weeks
期刊介绍: Journal of Diabetes Research is a peer-reviewed, Open Access journal that publishes research articles, review articles, and clinical studies related to type 1 and type 2 diabetes. The journal welcomes submissions focusing on the epidemiology, etiology, pathogenesis, management, and prevention of diabetes, as well as associated complications, such as diabetic retinopathy, neuropathy and nephropathy.
期刊最新文献
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