Gábor Kovács, Elemér Mohos, János Tibor Kis, Ádám Tabák, Péter Gerendy, Judit Pettkó, Dávid Nagy, Dávid Győrbíró, Zoltán Kaló
{"title":"肥胖症和 2 型糖尿病患者减肥手术的成本效益","authors":"Gábor Kovács, Elemér Mohos, János Tibor Kis, Ádám Tabák, Péter Gerendy, Judit Pettkó, Dávid Nagy, Dávid Győrbíró, Zoltán Kaló","doi":"10.1155/2023/9686729","DOIUrl":null,"url":null,"abstract":"<i>Aims</i>. The favourable effects of bariatric surgeries on body weight reduction and glucose control have been demonstrated in several studies. Additionally, the cost-effectiveness of bariatric surgeries has been confirmed in several analyses. The aim of the current analysis was to demonstrate the cost-effectiveness of bariatric surgeries in obese patients with type 2 diabetes in Hungary compared to conventional diabetes treatments based on economic modelling of published clinical trial results. <i>Materials and Methods</i>. Patients entered the simulation model at the age of 45 with <span><svg height=\"12.7178pt\" style=\"vertical-align:-3.42947pt\" version=\"1.1\" viewbox=\"-0.0498162 -9.28833 134.603 12.7178\" width=\"134.603pt\" xmlns=\"http://www.w3.org/2000/svg\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"><g transform=\"matrix(.013,0,0,-0.013,0,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,6.101,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,12.185,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,18.487,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,28.192,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,38.449,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,45.029,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,49.904,0)\"><use xlink:href=\"#g113-116\"></use></g><g transform=\"matrix(.013,0,0,-0.013,56.955,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,60.504,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,67.03,0)\"><use xlink:href=\"#g113-101\"></use></g><g transform=\"matrix(.013,0,0,-0.013,74.246,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,79.628,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,89.07,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,93.568,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,101.121,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,113.275,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,118.842,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,126.972,0)\"></path></g></svg><span></span><svg height=\"12.7178pt\" style=\"vertical-align:-3.42947pt\" version=\"1.1\" viewbox=\"138.1851838 -9.28833 13.083 12.7178\" width=\"13.083pt\" xmlns=\"http://www.w3.org/2000/svg\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"><g transform=\"matrix(.013,0,0,-0.013,138.235,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,144.475,0)\"></path></g></svg></span> kg/m<sup>2</sup> and type 2 diabetes. The model was performed from the public payer’s perspective, comparing sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) procedures to conventional care of diabetes. The results were provided separately for three BMI categories. <i>Results</i>. The base-case analysis demonstrated that both surgery types were dominant; i.e., they saved 17 064 to 24 384 Euro public payer expenditures and resulted in improved health outcomes (1.36 to 1.50 quality-adjusted life years gain (QALY)) in the three BMI categories. Bariatric surgeries extended the life expectancy and the disease-free survival times of all the investigated diabetes complications. All the scenario analyses confirmed the robustness of the base-case analysis, such that bariatric surgeries remained dominant compared to conventional diabetes treatments. <i>Conclusion</i>. The results of this cost-effectiveness analysis highlight the importance of bariatric surgeries as alternatives to conventional diabetes treatments in the obese population. Therefore, it is strongly recommended that a wider population has access to these surgeries in Hungary.","PeriodicalId":15576,"journal":{"name":"Journal of Diabetes Research","volume":"74 1","pages":""},"PeriodicalIF":3.6000,"publicationDate":"2023-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cost-Effectiveness of Bariatric Surgery in Patients Living with Obesity and Type 2 Diabetes\",\"authors\":\"Gábor Kovács, Elemér Mohos, János Tibor Kis, Ádám Tabák, Péter Gerendy, Judit Pettkó, Dávid Nagy, Dávid Győrbíró, Zoltán Kaló\",\"doi\":\"10.1155/2023/9686729\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<i>Aims</i>. The favourable effects of bariatric surgeries on body weight reduction and glucose control have been demonstrated in several studies. Additionally, the cost-effectiveness of bariatric surgeries has been confirmed in several analyses. The aim of the current analysis was to demonstrate the cost-effectiveness of bariatric surgeries in obese patients with type 2 diabetes in Hungary compared to conventional diabetes treatments based on economic modelling of published clinical trial results. <i>Materials and Methods</i>. Patients entered the simulation model at the age of 45 with <span><svg height=\\\"12.7178pt\\\" style=\\\"vertical-align:-3.42947pt\\\" version=\\\"1.1\\\" viewbox=\\\"-0.0498162 -9.28833 134.603 12.7178\\\" width=\\\"134.603pt\\\" xmlns=\\\"http://www.w3.org/2000/svg\\\" xmlns:xlink=\\\"http://www.w3.org/1999/xlink\\\"><g transform=\\\"matrix(.013,0,0,-0.013,0,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,6.101,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,12.185,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,18.487,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,28.192,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,38.449,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,45.029,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,49.904,0)\\\"><use xlink:href=\\\"#g113-116\\\"></use></g><g transform=\\\"matrix(.013,0,0,-0.013,56.955,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,60.504,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,67.03,0)\\\"><use xlink:href=\\\"#g113-101\\\"></use></g><g transform=\\\"matrix(.013,0,0,-0.013,74.246,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,79.628,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,89.07,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,93.568,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,101.121,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,113.275,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,118.842,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,126.972,0)\\\"></path></g></svg><span></span><svg height=\\\"12.7178pt\\\" style=\\\"vertical-align:-3.42947pt\\\" version=\\\"1.1\\\" viewbox=\\\"138.1851838 -9.28833 13.083 12.7178\\\" width=\\\"13.083pt\\\" xmlns=\\\"http://www.w3.org/2000/svg\\\" xmlns:xlink=\\\"http://www.w3.org/1999/xlink\\\"><g transform=\\\"matrix(.013,0,0,-0.013,138.235,0)\\\"></path></g><g transform=\\\"matrix(.013,0,0,-0.013,144.475,0)\\\"></path></g></svg></span> kg/m<sup>2</sup> and type 2 diabetes. The model was performed from the public payer’s perspective, comparing sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) procedures to conventional care of diabetes. The results were provided separately for three BMI categories. <i>Results</i>. The base-case analysis demonstrated that both surgery types were dominant; i.e., they saved 17 064 to 24 384 Euro public payer expenditures and resulted in improved health outcomes (1.36 to 1.50 quality-adjusted life years gain (QALY)) in the three BMI categories. Bariatric surgeries extended the life expectancy and the disease-free survival times of all the investigated diabetes complications. All the scenario analyses confirmed the robustness of the base-case analysis, such that bariatric surgeries remained dominant compared to conventional diabetes treatments. <i>Conclusion</i>. The results of this cost-effectiveness analysis highlight the importance of bariatric surgeries as alternatives to conventional diabetes treatments in the obese population. Therefore, it is strongly recommended that a wider population has access to these surgeries in Hungary.\",\"PeriodicalId\":15576,\"journal\":{\"name\":\"Journal of Diabetes Research\",\"volume\":\"74 1\",\"pages\":\"\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2023-12-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Diabetes Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1155/2023/9686729\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Diabetes Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1155/2023/9686729","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
Cost-Effectiveness of Bariatric Surgery in Patients Living with Obesity and Type 2 Diabetes
Aims. The favourable effects of bariatric surgeries on body weight reduction and glucose control have been demonstrated in several studies. Additionally, the cost-effectiveness of bariatric surgeries has been confirmed in several analyses. The aim of the current analysis was to demonstrate the cost-effectiveness of bariatric surgeries in obese patients with type 2 diabetes in Hungary compared to conventional diabetes treatments based on economic modelling of published clinical trial results. Materials and Methods. Patients entered the simulation model at the age of 45 with kg/m2 and type 2 diabetes. The model was performed from the public payer’s perspective, comparing sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) procedures to conventional care of diabetes. The results were provided separately for three BMI categories. Results. The base-case analysis demonstrated that both surgery types were dominant; i.e., they saved 17 064 to 24 384 Euro public payer expenditures and resulted in improved health outcomes (1.36 to 1.50 quality-adjusted life years gain (QALY)) in the three BMI categories. Bariatric surgeries extended the life expectancy and the disease-free survival times of all the investigated diabetes complications. All the scenario analyses confirmed the robustness of the base-case analysis, such that bariatric surgeries remained dominant compared to conventional diabetes treatments. Conclusion. The results of this cost-effectiveness analysis highlight the importance of bariatric surgeries as alternatives to conventional diabetes treatments in the obese population. Therefore, it is strongly recommended that a wider population has access to these surgeries in Hungary.
期刊介绍:
Journal of Diabetes Research is a peer-reviewed, Open Access journal that publishes research articles, review articles, and clinical studies related to type 1 and type 2 diabetes. The journal welcomes submissions focusing on the epidemiology, etiology, pathogenesis, management, and prevention of diabetes, as well as associated complications, such as diabetic retinopathy, neuropathy and nephropathy.