评估伴有便秘的帕金森病患者的双向肠脑轴和肛门直肠功能

Neurogastroenterology & Motility Pub Date : 2023-12-17 DOI:10.1111/nmo.14728

Yun Yan, Karunaratne Tennekoon, Audrey Eubanks, Anam Herekar, Dhanush Shimoga, Deepak Ayyala, Colin McLeod, Julie A. Kurek, John C. Morgan, Satish S. C. Rao, Amol Sharma

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摘要

帕金森病（Parkinson's disease，PD）是一种神经退行性运动障碍疾病，具有前驱症状和高发胃肠道（GI）症状，尤其是便秘。虽然帕金森病模型表明肠脑轴功能紊乱，但人们对其机理基础及其与胃肠道症状的相关性知之甚少。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Evaluation of bidirectional gut-brain axis and anorectal function in Parkinson's disease with constipation

Parkinson's disease (PD) is a neurodegenerative movement disorder with prodromal and highly prevalent gastrointestinal (GI) symptoms, especially constipation. Although PD models suggest gut-brain axis dysfunction, the mechanistic underpinnings and their correlation with GI symptoms are poorly understood.

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Neurogastroenterology & Motility

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