嗜酸性淋巴肉芽肿低剂量放疗的有效性和安全性

IF 1.9 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Alternative therapies in health and medicine Pub Date : 2024-08-01

Yudi You, Haiying Zhou, Xiulan Liu, Wei Zhang, Yuanzhe Xiao, Yabing Dong, Zhinan Liang, Chunmei Ni, Yujin Su

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引用次数: 0

摘要

目的：探讨低剂量放射疗法治疗嗜酸性淋巴肉芽肿的疗效和安全性：探讨低剂量放疗治疗嗜酸性淋巴肉芽肿的有效性和安全性：本研究共纳入20例确诊为嗜酸性淋巴肉芽肿的患者。所有患者均接受了低剂量三维适形调强放射治疗。我们分析了病灶的控制情况以及与放疗相关的不良反应：结果：低剂量放疗治疗嗜酸性淋巴肉芽肿的总体有效率为90%。放疗引起的I级和II级不良反应发生率分别为70%和30%。在中位 23.6 个月的随访期间，所有患者的病灶均在放疗靶区内得到控制。放疗后，4 名患者偶感瘙痒，1 名患者 3 年后在靶区外复发。随访期间未发现与放疗相关的长期严重不良反应：结论：低剂量放疗对嗜酸性淋巴肉芽肿有明显的治疗效果，且不良反应可接受。

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Effectiveness and Safety of Low-Dose Radiotherapy in Eosinophilic Lymphoid Granuloma.

Objective: To investigate the efficacy and safety of low-dose radiotherapy in treating eosinophilic lymphoid granuloma.

Method: This study included a total of 20 patients diagnosed with eosinophilic lymphoid granuloma. All patients underwent low-dose three-dimensional conformal intensity-modulated radiotherapy for their lesions. We analyzed the control status of the lesions and any adverse reactions related to radiotherapy.

Results: The overall effectiveness of low-dose radiotherapy in treating eosinophilic lymphoid granuloma was 90%. The incidence of grade I and grade II adverse reactions induced by radiotherapy was 70% and 30%, respectively. Over a median follow-up period of 23.6 months, all patients showed controlled lesions within the target delineation of radiotherapy. After radiotherapy, four patients experienced occasional pruritus, and one patient had a recurrence outside the target area three years later. No long-term severe adverse reactions related to radiotherapy were observed during the follow-up period.

Conclusions: Low-dose radiotherapy demonstrates an apparent therapeutic effect on eosinophilic lymphoid granuloma with acceptable adverse reactions.

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来源期刊

Alternative therapies in health and medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

0.90

自引率

0.00%

发文量

219

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