小 RNA 的表观遗传和基因调控功能。

Pub Date : 2024-03-29 DOI:10.5802/crbiol.131

Germano Cecere

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引用次数: 0

摘要

在这篇评论文章中，我总结了 2023 年 4 月 25 日在巴黎巴斯德研究所举行的 "向弗朗索瓦-格罗斯致敬 "活动中的发言。我讨论了在遗传信息和蛋白质翻译之间存在 RNA 中间体这一发现如何在过去几年中改变了我们对 RNA 在基因调控中作用的看法。我还将讨论新出现的范例，强调 RNA 在遗传信息中的作用与众所周知的 DNA 功能类似。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Epigenetic and gene regulatory functions of small RNAs.

In this review article, I summarize the intervention I made during the "Hommage à François Gros" held at the Institut Pasteur in Paris on the 25th of April, 2023. I discuss how the discovery of the existence of an RNA intermediate between genetic information and protein translation has changed our perspective on the role of RNA in gene regulation in these past years. I also discuss new emerging paradigms, highlighting the role of RNA in heritable information similar to the well-known DNA function.

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