生物标志物在紧急医疗状况诊断和管理中的应用

A. Aljefri, Mazen Saud Alharthi, Farhan Mufarreh Almadari, Hassan Abdualmohsin Alazwari, Zafer Ali Alshahrani, Abdullah Abdulelah Alanazi, Afnan Qasem Al Gadani, Ahmed Ali Aljawad, Faris Mohammed Qattan, Abdulrahman Hassan Shuraym, Aisha Nour Almutary
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引用次数: 0

摘要

在紧急情况下使用生物标记物代表着现代医疗保健的变革。这篇综述探讨了生物标记物在紧急情况下的影响,重点是它们如何提高诊断的准确性、洞察预后并帮助做出治疗决定。值得注意的是,肌钙蛋白(I 和 T)能有效诊断心肌梗塞,从而对心血管紧急情况进行有针对性的干预和风险评估。在败血症病例中,降钙素原有助于区分感染并影响治疗决策,这对全球抗击耐药性的努力至关重要。S100B 是一种在紧急情况下使用的生物标志物,有助于对脑损伤病例进行优先排序。为防止伤害,血清标志物如肌酐和胱抑素 C 可指导肝脏急症的干预措施。对于创伤和血液急症,D 二聚体和乳酸可提供预后信息。目前正在进行的研究正在探索生物标记物以及人工智能的整合,为未来提供了可喜的进步。生物标志物的临床意义凸显了我们对不断发展的急诊医学领域做出贡献的方法的承诺,并最终加强了对患者的护理。
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The use of biomarkers in the diagnosis and management of emergency medical conditions
The use of biomarkers in emergency situations represents a change in modern healthcare. This review examines their impact in emergencies focusing on how they improve the accuracy of diagnoses, provide insights into prognosis and aid in treatment decisions. Notably troponins (I and T) are effective in diagnosing myocardial infarction enabling targeted interventions and risk assessment for cardiovascular emergencies. In cases of sepsis procalcitonin helps distinguish infections and influences decisions about therapy, which is crucial for global efforts against resistance. S100B, a biomarker used in emergencies assists in prioritizing cases of brain injury. To prevent harm, serum markers like creatinine and cystatin C guide interventions for hepatic emergencies. For trauma and hematological emergencies D dimer and lactate provide prognostic information. Ongoing research is exploring biomarkers well as the integration of artificial intelligence offering promising advancements for the future. The clinical significance of biomarkers highlights a commitment to approaches that contribute to the ever-evolving field of emergency medicine and ultimately enhance patient care.
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