一名感染水痘的 13 岁女孩的附红细胞体视网膜炎--超声波擦洗术

Roko Škrabić, Neda Bjeliš, Višnja Kokić Maleš, Veselin Škrabić, Marko Šimunović
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摘要

水痘是一种传染性极强的传染病,可引起多种并发症。其中一种并发症是附睾睾丸炎,这种疾病非常罕见,文献中的描述也很少,因此很少被提及,诊断率低,治疗效果差。在本报告中,我们介绍了一例 13 岁男孩的病例,最初由一名感染科医生和一名小儿外科医生进行检查,诊断为水痘感染期间阴囊细菌超级感染。由于错误地使用抗生素治疗,他随后接受了儿科内分泌科医生的检查,被诊断为水痘并发症--附睾炎,并使用对乙酰氨基酚、冰袋和阴囊悬液进行治疗,因为错过了开始抗病毒治疗的 24 小时窗口期。实验室检查未发现感染迹象,而超声波检查显示右侧睾丸和附睾肿大,白膜增厚,睾丸旁有积液。随后的超声波随访显示,每次检查的结果都有所改善,一年后检查结果完全正常。随访期间,激素水平正常,精子数量也正常。然而,5 年后,精子活动能力下降,患者被诊断为无精子症。因此,我们必须强调水痘感染的作用及其对生殖健康的长期影响。考虑到抗病毒治疗效果不佳,预防并发症的效果仍令人怀疑,我们必须指出预防措施,包括接种疫苗和开发新的抗病毒方法。
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Epididimo-orhitis u 13-godišnjeg dječaka tokom varicella infekcije – ultrazvučno praćenje
Varicella is a highly contagious infectious disease that can cause various complications. One of them, epididymo-orchitis, is rare and poorly described in literature, and thus remains seldom thought of, under-diagnosed, and poorly treated. In this report we present the case of a 13-year-old boy initially examined by an infectologist and a pediatric surgeon under the diagnosis of a scrotal bacterial superinfection during a varicella infection. Wrongly treated with antibiotics, he was then examined by a pediatric endocrinologist, diagnosed with epididymoorchitis as a varicella complication, and treated with acetaminophen, ice packs and scrotum suspension, as the 24-hour window for antiviral therapy initiation was missed. Laboratory test showed no signs of infection, while ultrasonography showed enlargement of the right testicle and epididymis with thickening of tunica albuginea and paratesticular effusion. The ultrasound follow up then showed improvement with each examination and a year later a completely normal finding. The hormonal status was normal during the follow up, so was the sperm count. However, sperm mobility was reduced 5 years later and the patient was diagnosed with asthenozoospermia. Hence we must emphasize the role of a varicella infection and its ability to leave a long term consequence to reproductive health. Having in mind the diminished antiviral therapy and still doubtful complication prevention we have to point out the prevention measures, including vaccination and the development of new antiviral methods.
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