大脚趾远端趾骨软骨样纤维瘤的罕见病例

Sachin Sharma, Jyoti Kashyap, Ankur Sharma, Abhishek Dhiman
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摘要

软骨样纤维瘤(Chondromyxoid fibroma,CMF)是一种罕见的骨良性肿瘤,由软骨分化不完全引起,最早由 Jaffe 和 Lichtensein 于 1948 年描述。CMF占所有骨肿瘤的比例不到1%。组织病理学具有诊断意义,CMF 表现为纺锤形或星状细胞的分叶状区域,细胞中心为软骨或类粘蛋白物质,周边为高细胞性,有丰富的类纤维组织和少量多核破骨细胞(如巨细胞)。CMF 常见于长骨的干骺端,包括胫骨近端或股骨远端。手部和足部的短小管状骨是不常见的部位,脚趾占肿瘤的比例不到5%。我们介绍了一例左脚大脚趾远端指骨软骨样纤维瘤病例,患者为 35 岁男性。
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A rare case of chondromyxoid fibroma of distal phalanx of great toe
Chondromyxoid fibroma (CMF) is rare benign tumour of bone which are due to incomplete cartilage differentiation and first described by Jaffe and Lichtensein in 1948. CMF’s constitutes for less than 1% of all bone tumors. Histopathology is diagnostic and CMF show lobulated areas of spindle shaped or stellate cells with hypocellular center of chondroid or myxoid material and periphery is hypercellular with abundant fibromyxoid tissue and few multinucleated osteoclasts like giant cell. CMFs are commonly seen in metaphysis of long bones including proximal tibia or distal femur. Short tubular bones of hand and feet are uncommon sites and toes constitutes less than 5% of the tumors. We present a case of chondromyxoid fibroma of distal phalanx of left great toe in 35 years old male patient.
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