肉鸡日粮中作为抗生素替代品的合成生物补充剂

Samara de Castro Sousa, Gabriela Gomes da Silva, Francinete Alves de Sousa Moura, Daniela Rodrigues Pereira, L. Machado, L. S. Silva, Fabricio da Silva Delgado, R. M. Bezerra, Lrb Dourado
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摘要

抗生素会导致细菌产生抗药性,对公众健康构成重大威胁。合生素是抗生素的有效替代品,它能促进肠道微生物群的平衡,为有益菌的生长创造有利环境。本研究旨在评估在 1 到 42 日龄肉鸡日粮中添加合生元补充剂(+Poultry)作为抗生素替代品的效用。我们评估了它在两个阶段对生产性能的影响:1至21日龄和1至42日龄两个阶段的性能、消化率系数、代谢能、十二指肠和空肠形态测量、胴体产量和血液学参数。从第 1 天到第 42 天,共有 440 只罗斯 308 品系的雌雄肉用仔鸡被关在 2 平方米的笼子里。雏鸡被随机分配到四个处理中,每个处理有五个重复,每个重复由 22 只雏鸡组成,从而形成 20 个实验小区。处理组如下不添加抗生素或合生元的基础日粮(BD)、添加150ppm杆菌肽锌(BCZ)的基础日粮、添加0.5kg/t合生元的基础日粮和添加1kg/t合生元的基础日粮。本实验中使用的合生素添加剂(+Poultry)由 Nutri+ 公司提供,含有氨基酸、矿物质、益生菌培养物、益生添加剂和调味添加剂。在整个实验过程中,所有禽类每周都要接受一次卫生挑战,包括使用重复使用的垃圾和被垃圾污染的水。观察到处理对 1 至 21 日龄肉鸡饲料转化率的影响(P = 0.0100),表明与单独使用 BD 相比,使用 BD + 1kg/t 合生素的肉鸡饲料转化率有所提高。因此,我们建议在 1 至 21 日龄的肉鸡中添加 1 千克/吨的合生元补充剂,作为一种可行的抗生素替代品。经测试的合生元补充剂有望成为肉鸡各生命阶段日粮中的抗生素替代品,同时保持鸡的生产性能和健康。
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Synbiotic supplements as antibiotic alternatives in broiler diets
Antibiotics can contribute to bacterial resistance, posing a significant public health concern. Synbiotics represent an effective alternative to antibiotics, promoting the balance of intestinal microbiota and creating a conducive environment for beneficial bacteria growth. This study aimed to assess the utility of the synbiotic supplement (+Poultry) as a substitute for antibiotics in broiler diets from 1 to 42 days of age. We evaluated its impact on performance during two stages: 1 to 21 days and 1 to 42 days, digestibility coefficients, metabolizable energy, duodenum and jejunum morphometry, carcass yield, and hematological parameters. A total of 440 Ross 308 strain broiler chicks, both males and females, were accommodated in 2m² cages from day 1 to day 42. The birds were randomly assigned to four treatments, with each treatment having five replications consisting of 22 birds, thus forming 20 experimental plots. The treatment groups were as follows: Basal diet (BD) without the addition of antibiotics or synbiotics, BD with 150ppm zinc bacitracin (BCZ), BD with 0.5kg/t of synbiotic, and BD with 1kg/t of synbiotic. The synbiotic supplement (+Poultry) used in this experiment, provided by Nutri+, contained amino acids, minerals, probiotic culture, prebiotic additives, and flavoring additives. Throughout the experiment, all birds were subjected to a weekly sanitary challenge, which involved using reused litter and water contaminated with litter. Treatment effects were observed on feed conversion (P = 0.0100) of broilers aged 1 to 21 days, indicating improved feed conversion in broilers consuming BD + 1kg/t synbiotic compared to BD alone. Consequently, we recommend the incorporation of a synbiotic supplement at a rate of 1kg/t as a viable antibiotic replacement for chickens aged 1 to 21 days. The tested synbiotic supplement shows promise as an antibiotic alternative in broiler diets at all life stages, maintaining both performance and bird health.
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