病毒 RNA 是宿主与病毒之间关键性相互作用的枢纽

Q1 Biochemistry, Genetics and Molecular Biology Sub-cellular biochemistry Pub Date : 2023-01-01 DOI:10.1007/978-3-031-40086-5_13
Alfredo Castello, Louisa Iselin
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引用次数: 0

摘要

RNA 是病毒生命周期中的核心分子,它不仅是信使(m)RNA,还是基因组。鉴于这些关键作用,病毒 RNA 成为宿主-病毒相互作用的枢纽也就不足为奇了。然而,病毒 RNA 的相互作用组在很大程度上仍不为人知。本章将讨论细胞 RNA 结合蛋白在病毒感染中的重要性,以及为发现和描述这些蛋白而开发的新方法。
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Viral RNA Is a Hub for Critical Host-Virus Interactions.

RNA is a central molecule in the life cycle of viruses, acting not only as messenger (m)RNA but also as a genome. Given these critical roles, it is not surprising that viral RNA is a hub for host-virus interactions. However, the interactome of viral RNAs remains largely unknown. This chapter discusses the importance of cellular RNA-binding proteins in virus infection and the emergent approaches developed to uncover and characterise them.

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来源期刊
Sub-cellular biochemistry
Sub-cellular biochemistry Biochemistry, Genetics and Molecular Biology-Biochemistry
CiteScore
5.90
自引率
0.00%
发文量
33
期刊介绍: The book series SUBCELLULAR BIOCHEMISTRY is a renowned and well recognized forum for disseminating advances of emerging topics in Cell Biology and related subjects. All volumes are edited by established scientists and the individual chapters are written by experts on the relevant topic. The individual chapters of each volume are fully citable and indexed in Medline/Pubmed to ensure maximum visibility of the work.
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