组装细胞的工具:迈向细胞结构生物信息学时代。

Mengzhou Hu, Xikun Zhang, Andrew Latham, Andrej Šali, Trey Ideker, Emma Lundberg
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引用次数: 0

摘要

细胞由细胞器等大型组件组成,这些组件递归为更小的系统,如凝聚体和蛋白质复合物,形成了细胞的动态多尺度结构。最近的技术创新为系统分析亚细胞结构铺平了道路,对它们的作用和相互作用产生了前所未有的洞察力。在本次研讨会上,我们将讨论各种计算方法的进展、挑战与合作,以构建人类细胞的综合结构图。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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Tools for assembling the cell: Towards the era of cell structural bioinformatics.

Cells consist of large components, such as organelles, that recursively factor into smaller systems, such as condensates and protein complexes, forming a dynamic multi-scale structure of the cell. Recent technological innovations have paved the way for systematic interrogation of subcellular structures, yielding unprecedented insights into their roles and interactions. In this workshop, we discuss progress, challenges, and collaboration to marshal various computational approaches toward assembling an integrated structural map of the human cell.

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