Federica Giugliano, Laura Boldrini, Jacopo Uliano, Edoardo Crimini, Ida Minchella, Giuseppe Curigliano
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引用次数: 0
摘要
肿瘤学文献对营养模式对乳腺癌(BC)发病风险的影响进行了深入研究,包括饮食类型和热量摄入。据报道,肥胖和体重指数升高是导致乳腺癌发生的关键风险因素,而评估癌症患者热量摄入和营养模式影响的肿瘤学领域也在不断扩大。据报道,根据临床前模型,限制热量摄入和模拟快速进食方案可改善生存预后。此外,新出现的临床证据也为采用新的新陈代谢方法治疗 BC 铺平了道路,这些方法既可以作为既有疗法的补充,也可以作为替代选择。在本章中,我们将讨论通过营养干预对 BC 患者进行代谢控制的主要策略,这是癌症治疗的一个创新领域。
Fast Mimicking Diets and Other Innovative Nutritional Interventions to Treat Patients with Breast Cancer.
The impact of nutritional patterns on the risk of breast cancer (BC) is well investigated in the oncology literature, including the type of diets and caloric intake. While obesity and elevated body mass index are well-reported critical risk factors of BC occurrence, there is an expanding area of oncology assessing the impact of caloric intake and nutritional patterns in patients with cancer. Caloric restriction and fast mimicking alimentary regimens have been consistently reported to improve survival outcomes based on preclinical models. Moreover, emerging clinical evidence has paved the way for new metabolic approaches for the treatment of BC, in addition to the established therapeutic arsenal or as alternative options. In this chapter, our aim is to discuss the principal strategies of metabolic manipulation through nutritional interventions for patients with BC as an innovative area of cancer therapy.