小黄牛对甲苯噻嗪和芬太尼镇痛的心脏和理化反应

IF 0.2 4区 农林科学 Q4 AGRICULTURE, DAIRY & ANIMAL SCIENCE Buffalo Bulletin Pub Date : 2023-12-31 DOI:10.56825/bufbu.2023.4244266
G. Singh, Anil Gattani, Ajeet Kumar, Anil Kumar
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引用次数: 0

摘要

小手术干预和安全束缚需要镇静和镇痛,尤其是对水牛等狂暴的动物,这可以通过使用适当的镇静和镇痛药物组合来实现。将甲苯噻嗪与阿片类药物结合使用,是实现牛马镇静和镇痛的有效方法。本研究选取了六头表面健康、有轻微伤口的水牛。通过静脉注射芬太尼(每公斤体重 5 微克)加羟嗪(每公斤体重 0.05 毫克)来实现镇静。在用药后的不同时间间隔观察生理、血液生化和心电图参数。用药后,心率、收缩压、舒张压、平均动脉血压、血红蛋白和充盈细胞体积均明显下降。呼吸频率在 30 分钟间隔内明显增加。PR 间期和 QT 间期分别在观察期的 20 分钟和 15 分钟时明显增加,而 ST 段的持续时间在 15 分钟至 30 分钟时明显增加。本研究表明,在观察期间,联合用药对心肺、血液生化和生理参数没有有害影响。
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Cardiac and physico-chemical responses to xylazine and fentanyl analgesia in Bubalus bubalis
The minor surgical intervention and safe restraining requires sedation and analgesia especially in furious animals like buffaloes which can be achieved by using proper combination of sedative and analgesic drugs. The combination of xylazine with opioids is an effective way to achieve sedation and analgesia in cattle and horses. Six apparently healthy buffaloes having minor wounds were included in the present study. The sedation was accomplished by fentanyl (5 µg per kg b.wt) plus xylazine (0.05 mg per kg b.wt) intravenously. Physiological, hematobiochemical and electrocardiographic parameters were observed at different time interval after the administration of drugs. Following the administration of medicine, there was a significant reduction in heart rate, systolic blood pressure, diastolic blood pressure, mean arterial blood pressure, hemoglobin, and packed cell volume. Respiration rate increased significantly at 30 minutes interval. PR interval and QT interval increased significantly at 20 minutes and 15 minutes respectively of the observation period, whereas a significant increase in the duration of ST segment was noticed from 15 minutes to 30 minutes. The present study revealed that the drug combination has no deleterious effects on cardiopulmonary, hematobiochemical and physiological parameters during the observation period.
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来源期刊
Buffalo Bulletin
Buffalo Bulletin AGRICULTURE, DAIRY & ANIMAL SCIENCE-
CiteScore
0.50
自引率
0.00%
发文量
53
审稿时长
>12 weeks
期刊介绍: Buffalo Bulletin is published quarterly in January-March, April-June, July-September and October-December. Contributions on any aspect of research or development, progress reports of projects and news on buffalo will be considered for publication in the bulletin.
期刊最新文献
Characteristics of the karyotype of Ukrainian buffalos Uterine torsion in buffaloes - A complete review Cardiac and physico-chemical responses to xylazine and fentanyl analgesia in Bubalus bubalis Identification of Chlamydia abortus and Chlamydia pecorum in water buffaloes (Bubalus bubalis) and cows cohabitating the same herd Physical and bio-control methodologies for integrated management of buffalo fly-Haematobia exigua (Diptera: Muscidae)
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