小黄牛对甲苯噻嗪和芬太尼镇痛的心脏和理化反应

IF 0.2 4区 农林科学 Q4 AGRICULTURE, DAIRY & ANIMAL SCIENCE Buffalo Bulletin Pub Date : 2023-12-31 DOI:10.56825/bufbu.2023.4244266
G. Singh, Anil Gattani, Ajeet Kumar, Anil Kumar
{"title":"小黄牛对甲苯噻嗪和芬太尼镇痛的心脏和理化反应","authors":"G. Singh, Anil Gattani, Ajeet Kumar, Anil Kumar","doi":"10.56825/bufbu.2023.4244266","DOIUrl":null,"url":null,"abstract":"The minor surgical intervention and safe restraining requires sedation and analgesia especially in furious animals like buffaloes which can be achieved by using proper combination of sedative and analgesic drugs. The combination of xylazine with opioids is an effective way to achieve sedation and analgesia in cattle and horses. Six apparently healthy buffaloes having minor wounds were included in the present study. The sedation was accomplished by fentanyl (5 µg per kg b.wt) plus xylazine (0.05 mg per kg b.wt) intravenously. Physiological, hematobiochemical and electrocardiographic parameters were observed at different time interval after the administration of drugs. Following the administration of medicine, there was a significant reduction in heart rate, systolic blood pressure, diastolic blood pressure, mean arterial blood pressure, hemoglobin, and packed cell volume. Respiration rate increased significantly at 30 minutes interval. PR interval and QT interval increased significantly at 20 minutes and 15 minutes respectively of the observation period, whereas a significant increase in the duration of ST segment was noticed from 15 minutes to 30 minutes. The present study revealed that the drug combination has no deleterious effects on cardiopulmonary, hematobiochemical and physiological parameters during the observation period.","PeriodicalId":9393,"journal":{"name":"Buffalo Bulletin","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cardiac and physico-chemical responses to xylazine and fentanyl analgesia in Bubalus bubalis\",\"authors\":\"G. Singh, Anil Gattani, Ajeet Kumar, Anil Kumar\",\"doi\":\"10.56825/bufbu.2023.4244266\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The minor surgical intervention and safe restraining requires sedation and analgesia especially in furious animals like buffaloes which can be achieved by using proper combination of sedative and analgesic drugs. The combination of xylazine with opioids is an effective way to achieve sedation and analgesia in cattle and horses. Six apparently healthy buffaloes having minor wounds were included in the present study. The sedation was accomplished by fentanyl (5 µg per kg b.wt) plus xylazine (0.05 mg per kg b.wt) intravenously. Physiological, hematobiochemical and electrocardiographic parameters were observed at different time interval after the administration of drugs. Following the administration of medicine, there was a significant reduction in heart rate, systolic blood pressure, diastolic blood pressure, mean arterial blood pressure, hemoglobin, and packed cell volume. Respiration rate increased significantly at 30 minutes interval. PR interval and QT interval increased significantly at 20 minutes and 15 minutes respectively of the observation period, whereas a significant increase in the duration of ST segment was noticed from 15 minutes to 30 minutes. The present study revealed that the drug combination has no deleterious effects on cardiopulmonary, hematobiochemical and physiological parameters during the observation period.\",\"PeriodicalId\":9393,\"journal\":{\"name\":\"Buffalo Bulletin\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2023-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Buffalo Bulletin\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.56825/bufbu.2023.4244266\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"AGRICULTURE, DAIRY & ANIMAL SCIENCE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Buffalo Bulletin","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.56825/bufbu.2023.4244266","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"AGRICULTURE, DAIRY & ANIMAL SCIENCE","Score":null,"Total":0}
引用次数: 0

摘要

小手术干预和安全束缚需要镇静和镇痛,尤其是对水牛等狂暴的动物,这可以通过使用适当的镇静和镇痛药物组合来实现。将甲苯噻嗪与阿片类药物结合使用,是实现牛马镇静和镇痛的有效方法。本研究选取了六头表面健康、有轻微伤口的水牛。通过静脉注射芬太尼(每公斤体重 5 微克)加羟嗪(每公斤体重 0.05 毫克)来实现镇静。在用药后的不同时间间隔观察生理、血液生化和心电图参数。用药后,心率、收缩压、舒张压、平均动脉血压、血红蛋白和充盈细胞体积均明显下降。呼吸频率在 30 分钟间隔内明显增加。PR 间期和 QT 间期分别在观察期的 20 分钟和 15 分钟时明显增加,而 ST 段的持续时间在 15 分钟至 30 分钟时明显增加。本研究表明,在观察期间,联合用药对心肺、血液生化和生理参数没有有害影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Cardiac and physico-chemical responses to xylazine and fentanyl analgesia in Bubalus bubalis
The minor surgical intervention and safe restraining requires sedation and analgesia especially in furious animals like buffaloes which can be achieved by using proper combination of sedative and analgesic drugs. The combination of xylazine with opioids is an effective way to achieve sedation and analgesia in cattle and horses. Six apparently healthy buffaloes having minor wounds were included in the present study. The sedation was accomplished by fentanyl (5 µg per kg b.wt) plus xylazine (0.05 mg per kg b.wt) intravenously. Physiological, hematobiochemical and electrocardiographic parameters were observed at different time interval after the administration of drugs. Following the administration of medicine, there was a significant reduction in heart rate, systolic blood pressure, diastolic blood pressure, mean arterial blood pressure, hemoglobin, and packed cell volume. Respiration rate increased significantly at 30 minutes interval. PR interval and QT interval increased significantly at 20 minutes and 15 minutes respectively of the observation period, whereas a significant increase in the duration of ST segment was noticed from 15 minutes to 30 minutes. The present study revealed that the drug combination has no deleterious effects on cardiopulmonary, hematobiochemical and physiological parameters during the observation period.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Buffalo Bulletin
Buffalo Bulletin AGRICULTURE, DAIRY & ANIMAL SCIENCE-
CiteScore
0.50
自引率
0.00%
发文量
53
审稿时长
>12 weeks
期刊介绍: Buffalo Bulletin is published quarterly in January-March, April-June, July-September and October-December. Contributions on any aspect of research or development, progress reports of projects and news on buffalo will be considered for publication in the bulletin.
期刊最新文献
Successful pervaginal management of Schistosoma reflexus in buffalo: A case report Electrocardiography markers in hypocalcaemia of peripartum buffaloes Assessment of oxidative stress parameters in summer anestrous buffaloes exhibiting differential fertility following melatonin implants treatment Age but not sex is a primary predisposing factor for Ascariosis in buffalo calves: An evidence from Mumbai, India Oseophageal obstruction and its surgical management in 4 buffaloes- A case study
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1