内毒素血症条件下药用肠内营养和菊粉对纠正术后肠道运动失调和微生物增生症疗效的实验研究

N. S. Tropskaya, E. A. Kislyаkova, I. G. Vilkova, Yu. V. Gurman, O. S. Kislitsyna, Ye. N. Borodina, T. V. Chernen'kaya, T. S. Popova
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引用次数: 0

摘要

提出了一种纠正肠道运动失调和微生物变性的方案。在大鼠身上进行的实验包括依次在空肠内给予药物性肠内营养(Intestamine,含有谷氨酰胺和三丁烯)和菊粉(一种益生菌制剂)。在发生内毒素血症的术后阶段应用该方案,可防止空肠内细菌过度生长,刺激出现推进性蠕动,消除病理性蠕动模式,并促进小肠协调蠕动的早日恢复。
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Experimental Study of the Efficacy of Pharmaconutrient Enteral Nutrition and Inulin in the Correction of Intestinal Motor Disorders and Microbiocenosis in the Postoperative Period Under Endotoxemia Conditions
A scheme for correcting intestinal motor disorders and microbiocenosis is proposed. Experiments on rats included a sequential jejunum administration of pharmaconutrient enteral nutrition (Intestamine, containing glutamine and tributyrin) and inulin, a prebiotic preparation. The application of this scheme in the postoperative period in the setting of endotoxemia prevents excessive bacterial growth in the jejunum, stimulates the appearance of propulsive peristalsis, eliminates pathological motility patterns and promotes early recovery of coordinated peristalsis of the small intestine.
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