Hpv prevalence and risk of premalignant and malignant lesions in women with asymptomatic cervical erosion: A population-based study

Objective: To evaluate the prevalence of HPV and the risk of the cervical premalignant and malignant diseases in women with cervical erosion. Material and Methods: The results of 32649 women who were screened for cervical cancer between January 2014 and December 2019 were retrospectively analyzed. The results of HPV positive and HPV negative women with cervical erosion were compared. Kruskal-Wallis test and Chi-square test was used to compare of data between the groups. Results: Of the 32649 women who were screened for cervical cancer, 2566 had cervical erosion and 1585 (4.85%) had HPV positivity. HPV was found to be positive in 126 (4.91%) women with cervical erosion and no significant difference in the incidence of HPV positivity in asymptomatic women with and without cervical erosion (p=0.112). As in the general population, Hpv 16 and 18 were found to be most common in women with cervical erosions. Abnormal cervical cytology was found in 217 (0.72%) women without cervical erosion and 31 (1.21%) women with cervical erosion, which was significantly higher than in women without cervical erosion (p=0.045). There was no significant difference between those with and without cervical erosion in terms of CIN 1, CIN 2, CIN 3, LSIL, HSIL in situ cancer and total abnormal cervical pathology results. Conclusion: The incidence of HPV and the likelihood of cervical pathology in asymptomatic women with cervical erosion do not differ from the general population.