一名免疫功能正常的患者因水痘-带状疱疹病毒脑膜脑炎而出现血栓性血小板减少性紫癜

IF 1 Q4 INFECTIOUS DISEASES Journal of Global Infectious Diseases Pub Date : 2023-10-01 DOI:10.4103/jgid.jgid_241_22

Zachary Mostel, B. Nguyen, Louis Costanzo, Sarah Bankhead, Parinaz Ayat, Harsha Taluru, Anoop Puskoor, Zahra Ahmed, Edwin Chiu, A. El Sehamy, David Nathaniel Smith

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引用次数: 0

摘要

水痘-带状疱疹病毒（VZV）可导致免疫系统完好或受损的个体出现不同的疾病状态。脑膜脑炎和血栓性血小板减少性紫癜（TTP）都是与 VZV 相关的不常见的危及生命的疾病。关于 VZV 引起的 TTP 的报道很少，这可能是首例通过腰椎穿刺证实的 VZV 脑膜脑炎引起的 TTP。文献倾向于强调这种病理变化大多发生在免疫功能低下的宿主身上。在这里，我们介绍了一例由 VZV 脑膜脑炎引起的 TTP，患者免疫功能正常。

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Thrombotic thrombocytopenic purpura due to varicella-zoster virus meningoencephalitis in an immunocompetent patient

Varicella-zoster virus (VZV) can cause variable disease states in individuals with intact and compromised immune systems. Both meningoencephalitis and thrombotic thrombocytopenic purpura (TTP) are uncommon, life-threatening entities associated with VZV. There are few reported cases of TTP due to VZV and this may be the first case of TTP due to VZV meningoencephalitis confirmed through lumbar puncture. The literature tends to emphasize that this pathology mostly occurs in immunocompromised hosts. Here, we present a unique case of TTP due to VZV meningoencephalitis in a patient that was immunocompetent.

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来源期刊

Journal of Global Infectious Diseases INFECTIOUS DISEASES-

CiteScore

3.30

自引率

0.00%

发文量

审稿时长

29 weeks

期刊介绍： JGID encourages research, education and dissemination of knowledge in the field of Infectious Diseases across the world thus promoting translational research by striking a synergy between basic science, clinical medicine and public health. The Journal intends to bring together scientists and academicians in Infectious Diseases to promote translational synergy between Laboratory Science, Clinical Medicine and Public Health. The Journal invites Original Articles, Clinical Investigations, Epidemiological Analysis, Data Protocols, Case Reports, Clinical Photographs, review articles and special commentaries. Students, Residents, Academicians, Public Health experts and scientists are all encouraged to be a part of this initiative by contributing, reviewing and promoting scientific works and science.