一名年轻男子心肌炎表现为冠状动脉非梗阻性心肌梗死(MINOCA):病例报告。

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL Acta medica Indonesiana Pub Date : 2023-10-01
Giovanni Reynaldo, Rachmat Hamonangan, Princella Monica
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引用次数: 0

摘要

冠状动脉无阻塞性心肌梗死(MINOCA)是一种独特的疾病,临床表现为急性心肌梗死,但血管造影却没有发现明显的冠状动脉阻塞。在此,我们报告了一名入院前 3 小时出现胸痛并持续发热 2 天的 17 岁男性患者。心电图检查显示 II、III、aVF 和 V3-V6 导联 ST 段抬高。实验室检查结果显示白细胞水平正常,为 9850 个/微升,肌钙蛋白升高,为 3.55 纳克/毫升,定量 CRP 升高,为 46 毫克/升。冠状动脉造影显示,左前降支动脉、左侧环状动脉和右冠状动脉狭窄20-30%,而在典型的急性心肌损伤中,血管造影显示冠状动脉狭窄>50%。额外的心脏核磁共振检查显示,该患者符合路易斯湖心肌炎标准,并进一步发现左心室侧壁急性心肌水肿,左心室射血分数为 59.73%。由于研究人员仍在研究 MINOCA 的定义,目前对 MINOCA 的病因、病理生理学、临床特征或具体表型的了解也很有限。在诊断 MINOCA 时,需要采取循序渐进的诊断方法,并随后排除鉴别诊断。
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Myocarditis Presenting as Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) in a Young Man: A Case Report.

Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a unique disorder that manifests as an acute myocardial infarction clinically without overt coronary arteries obstruction on angiography. Herein, we report a 17-year-old male presented with a chest pain occurring 3 hours before admission and fever lasting for 2 days. Electrocardiogram examination showed ST elevation in lead II, III, aVF and V3-V6. Laboratory tests results showed a normal leukocyte level of 9850/µL, an elevated troponin of 3.55 ng/mL and an elevated quantitative CRP of 46 mg/L. Coronary angiography performed, indicating 20-30% stenosis of the left anterior descending artery, left circumflex artery and right coronary artery, whereas in typical acute myocardial injury, angiography shows >50% coronary stenosis. Additional cardiac MRI examination showed a fulfillment of Lake Louis Criteria for myocarditis, with further findings of acute myocardial edema in the lateral wall of left ventricle, with left ventricle ejection fraction of 59.73%. As researchers are still working on the definition of MINOCA, present knowledge of the causes, pathophysiology, clinical features, or specific phenotypes of MINOCA is also limited. A stepwise diagnostic approach is needed to diagnose MINOCA, with subsequent differential diagnosis exclusion.

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来源期刊
Acta medica Indonesiana
Acta medica Indonesiana MEDICINE, GENERAL & INTERNAL-
CiteScore
2.30
自引率
0.00%
发文量
61
审稿时长
12 weeks
期刊介绍: Acta Medica Indonesiana – The Indonesian Journal of Internal Medicine is an open accessed online journal and comprehensive peer-reviewed medical journal published by the Indonesian Society of Internal Medicine since 1968. Our main mission is to encourage the novel and important science in the clinical area in internal medicine. We welcome authors for original articles (research), review articles, interesting case reports, special articles, clinical practices, and medical illustrations that focus on the clinical area of internal medicine. Subjects suitable for publication include, but are not limited to the following fields of: -Allergy and immunology -Emergency medicine -Cancer and stem cells -Cardiovascular -Endocrinology and Metabolism -Gastroenterology -Gerontology -Hematology -Hepatology -Tropical and Infectious Disease -Virology -Internal medicine -Psychosomatic -Pulmonology -Rheumatology -Renal and Hypertension -Thyroid
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