良性鳞状上皮细胞瘤伴广泛囊性鳞状增生,临床表现为恶性鳞状上皮细胞瘤

Mousmi Agrawal, Nighat Hussain, R. Ramchandani, Amit Kumar Chowhan
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引用次数: 0

摘要

皮样瘤是一种非常罕见的纤维上皮性病变,占所有原发性乳腺肿瘤的 0.3%-1%,高发年龄在 40-50 岁左右。皮样肿瘤分为三种类型:良性肿瘤、边缘型肿瘤和恶性肿瘤。蜕变在这些肿瘤中非常罕见,可涉及上皮或基质成分。基质变性包括软骨、骨质或脂肪变化。上皮变性包括杏仁样变或鳞状变。大约10%的鳞状细胞瘤表现为鳞状变。我们报告了一例 47 岁患者的病例,患者右侧乳房有一个大肿块,大小为 16 厘米 × 15 厘米 × 11 厘米,占据了四个象限。临床表现为恶性蝶形瘤。但在显微镜下,它是良性蝶形瘤,有广泛的囊性鳞状化生。
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Benign Phyllodes Tumor with Extensive Cystic Squamous Metaplasia, Clinically Presenting as Malignant Phyllodes
Phyllodes tumor are very rare fibroepithelial lesions which comprises 0.3%–1% of all primary breast tumors with peak age around 40–50 years. Phyllodes tumor are classified ino three types: Benign, borderline and malignant tumors. Metaplastic change is very rare in these tumors and can involve both epithelial or stromal components. Stromal metaplastic changes include cartilage, bony or fatty change. Epithelial metaplastic changes include apocrine or squamous change. About 10% of phyllodes tumor show squamous metaplasia. We report a case of 47-year-old patient presenting with large lump in right breast measuring 16 cm × 15 cm × 11 cm, occupying all four quadrants. Clinically, it appeared as malignant phyllodes. But, microscopically, it was benign phyllodes tumor having extensive cystic squamous metaplasia.
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1.90
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46
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