新型支架治疗坐骨神经痛的疗效和尸体解剖以检查坐骨神经的游离情况

Kyle Callahan, Dale Dellacqua
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背景/目的:坐骨神经痛影响着近一半的美国人,通常会使人衰弱,导致剧烈疼痛,限制日常生活活动。目前还没有人尝试过使用支具来减轻疼痛。在这项研究中,我们试图找出一种新型支架能否减轻坐骨神经痛患者的疼痛,并降低其令人烦恼的症状程度。此外,本研究还利用尸体解剖来了解坐骨神经在下肢操作时是如何伸展和紧张的。方法:14 名患者自我报告了支撑前后的疼痛、功能和困扰程度。使用 Excel 数据分析工具进行统计测试。解剖一具尸体(2 个下肢),显示髋部和膝部的坐骨神经以及踝部的胫神经。利用一个固定的针和初始距离测量偏移量,操纵腿部,并测量与针的最终距离。最终,偏移量被认为是最终距离减去与固定针的初始距离。结果:支具降低了视觉模拟量表(VAS)评分,增加了患者报告结果,并降低了坐骨神经痛困扰指数。初次就诊和就诊后 7 天的 VAS 值与穿戴支具后的有明显差异,但就诊后 21 天或 42 天的差异不大。坐骨神经偏移在脚踝处最大。结论和潜在影响:使用护具可减轻疼痛程度,提高功能性,并减轻症状的困扰程度。远端神经在操作时移动更多,因此比近端神经更容易受到牵拉。解剖数据说明了支架如何使肢体处于促进神经 "分离 "的位置,从而缓解坐骨神经痛。还需要更多的尸体数据。
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Efficacy of Novel Bracing for Treating Sciatica and Cadaveric Dissection to Examine Excursion of the Sciatic Nerve
Background/Objective:Sciatica affects nearly half of all Americans and can often become debilitating, leading to severe pain that can limit performing activities of daily living. Brace application has not been tried for alleviation of pain. In this study, we seek to find if a novel brace can decrease pain and decrease bothersome level of symptoms for those suffering from sciatica. In addition, this study utilizes a cadaveric dissection to understand how the sciatic nerve stretches and tensions upon lower limb manipulation. Methods:Fourteen patients self-reported pain, functionality, and bothersome levels pre- and post-bracing. Excel’s data analysis tool was utilized to run statistical tests. One cadaver (2 lower limbs) was dissected, revealing the sciatic nerve at the hip and knee, while tibial nerve at the ankle. Excursion was measured utilizing a fixed pin and an initial distance, the leg manipulated, and final distance from pin measured. Ultimately, excursion was deemed final distance minus initial distance from the pin. Results:The brace decreases Visual Analogue Scale (VAS) scores, increases Patient Reported Outcomes, and decreases Sciatica Bothersome Indexes. There was a significant difference in VAS pre- versus post-brace values at initial and 7-day post-visit but not at 21- or 42-day postvisit. Sciatic nerve excursion was greatest at the ankle. Conclusion and Potential Impact:Brace use decreases pain levels, increases functionality, and decreases bothersome level of symptoms. The distal nerve moves more upon manipulation and therefore is more prone to tensioning than the proximal nerve. Dissection data illustrates how the brace positions the limb in a way that promotes “detensioning” of the nerve, alleviating sciatica. More cadaver data is needed.
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