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引用次数: 0
摘要
封面内页:由人类 2N4R tau(品红色)组成的 tau 包膜包裹的axol 稳定微管的全内反射显微镜图像。Tau 包膜排除了人类 MAP4(绿色)的结合,从而在体外沿着单个微管形成了不同的 MAP 覆盖域。
ON THE INNER FRONT COVER: Total internal reflection microscopy image of taxol-stabilized microtubules coated in tau envelopes composed of human 2N4R tau (magenta). Tau envelopes exclude the binding of human MAP4 (green), resulting in distinct MAP-covered domains along single microtubules in vitro.
Credit: Richard J. McKenney, University of California, Davis.
期刊介绍:
Cytoskeleton focuses on all aspects of cytoskeletal research in healthy and diseased states, spanning genetic and cell biological observations, biochemical, biophysical and structural studies, mathematical modeling and theory. This includes, but is certainly not limited to, classic polymer systems of eukaryotic cells and their structural sites of attachment on membranes and organelles, as well as the bacterial cytoskeleton, the nucleoskeleton, and uncoventional polymer systems with structural/organizational roles. Cytoskeleton is published in 12 issues annually, and special issues will be dedicated to especially-active or newly-emerging areas of cytoskeletal research.