赞比亚卢萨卡 Chawama 一级医院 15 岁及以上结核病患者中与结核病治疗效果相关的因素。

IF 2.3 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Global Public Health Pub Date : 2024-01-01 Epub Date: 2024-01-29 DOI:10.1080/17441692.2024.2307979
Rodgers Chilyabanyama, Nathan Kamanga, Jim Nkukwa Mwandia
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引用次数: 0

摘要

结核病是全球关注的健康问题,对社区、卫生系统和经济都有影响。本研究采用回顾性设计,以 2020 年通知的患者为重点,评估了赞比亚卢萨卡 Chawama 一级医院 15 岁以上患者的结核病治疗效果。样本采用描述性统计方法进行描述。采用皮尔逊卡方检验和物流回归分析影响治疗结果的患者特征,显著性水平为 5%。在 404 名参与者中,83.4% 的人获得了成功的治疗结果。性别、患者类型、肺结核类型、艾滋病病毒感染状况和短期直接观察治疗计划对治疗结果的影响存在差异,但差异不显著。与 15-24 岁人群相比,65 岁以上人群的成功几率低 72.4%(OR (95% CI):0.276 (0.086-0.881),p = .030)。同样,在对其他变量进行调整后,成功几率降低了 72.9%(AOR (95% CI):0.271 (0.083-0.882),p = .030)。这项研究取得了令人鼓舞的 83.4% 的结核病成功率,这凸显了为达到世界卫生组织目标而进行改进的潜力。值得注意的是,65 岁以上患者的治疗成功率较低,这表明需要进行重点干预。建议对老年患者给予特别关注,并采取有针对性的结核病计划干预措施。
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Factors associated with tuberculosis treatment outcomes among TB patients aged 15 years and older at chawama level one hospital in Lusaka, Zambia.

Tuberculosis is a global health concern n impacting communities, health systems, and economies This study assessed the TB treatment outcomes among individuals aged 15+ at Chawama first level hospital in Lusaka, Zambia, using a retrospective design focussing on individuals notified in 2020. The sample was described using descriptive statistics. The Pearson Chi-square test and logistics regression were used to analyse the characteristics of the patients influencing the treatment outcomes at 5% significant level. Out of 404 participants, 83.4% of them had successful treatment outcomes. Varied outcomes were noted in sex, patient type, TB type, HIV status, and DOT plan, but lacked significance. Odds of success were lower by 72.4% for those aged 65+ compared to those aged 15-24 years (OR (95% CI): 0.276 (0.086-0.881), p = .030). Similarly, after adjusting for other variables, the odds of success were lower by 72.9% (AOR (95% CI): 0.271 (0.083-0.882), p = .030). This study yielded an encouraging 83.4% TB success rate highlighting the potential for improvement to meet WHO targets. Notably, individuals aged 65+ showed a distinct pattern with lower treatment success odds, suggesting a need for focussed interventions. Special attention to elderly patients and targeted TB program interventions are recommended.

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来源期刊
Global Public Health
Global Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
6.50
自引率
3.00%
发文量
120
期刊介绍: Global Public Health is an essential peer-reviewed journal that energetically engages with key public health issues that have come to the fore in the global environment — mounting inequalities between rich and poor; the globalization of trade; new patterns of travel and migration; epidemics of newly-emerging and re-emerging infectious diseases; the HIV/AIDS pandemic; the increase in chronic illnesses; escalating pressure on public health infrastructures around the world; and the growing range and scale of conflict situations, terrorist threats, environmental pressures, natural and human-made disasters.
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