复方生物相同激素疗法的伦理评估。

IF 2.9 4区医学 Q1 OBSTETRICS & GYNECOLOGY Climacteric Pub Date : 2024-06-01 Epub Date: 2024-01-30 DOI:10.1080/13697137.2024.2306272

R P Kauffman, E J MacLaughlin, L A Courtney, D D Vineyard

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引用次数: 0

摘要

尽管美国食品和药物管理局批准了许多不同配方和剂量的激素产品，但复方生物相同激素疗法（cBHT）的使用仍在不断普及。cBHT 的支持者提出的许多主张都没有经过适当设计的研究证实。人们对 cBHT 的纯度、功效、生物利用度和安全性提出了合理的关切。由于病人的福祉是卫生专业人员的首要职责，推广 cBHT 并将其作为第一线疗法的处方违反了医疗和药学实践中的一些道德原则，在没有令人信服的理由的情况下，应予以劝阻。

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An ethical assessment of compounded bioidentical hormone therapy.

The use of compounded bioidentical hormone therapy (cBHT) continues to grow in popularity despite the availability of many US Food and Drug Administration-approved hormone products produced in different formulations and dosages. Numerous claims made by proponents of cBHT are not substantiated by properly designed studies. Valid concerns about purity, efficacy, bioavailability and safety of cBHT have been raised. Since patient welfare is the first duty of health professionals, promoting and prescribing cBHT as first-line therapy violates a number of ethical tenets of medical and pharmacy practice and should be discouraged without a compelling reason.

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来源期刊

Climacteric 医学-妇产科学

CiteScore

1.70

自引率

7.10%

发文量

审稿时长

1 months

期刊介绍： Climacteric is the official journal of the International Menopause Society (IMS). As an international peer-reviewed journal it publishes original research and reviews of all aspects of aging in women. Climacteric was founded by the IMS in 1998 and today has become a leading journal in the publication of peer-reviewed papers on the menopause, climacteric and mid-life health. Topics covered include endocrine changes, symptoms attributed to the menopause and their treatment, hormone replacement and alternative therapies, lifestyles, and the counselling and education of peri- and postmenopausal women. Climacteric, published bimonthly, also features regular invited reviews, editorials and commentaries on recent developments. The editorial review board of Climacteric includes leading scientific and clinical experts in the field of midlife medicine and research and is headed by its Editor-in-Chief, Professor Rod Baber of Australia. He and his team of Associate Editors act independently to set a clear editorial policy, co-ordinate peer review, and ensure a rapid response to submitted papers.