{"title":"由克隆造血驱动的单核细胞衍生小胶质细胞导致的与年龄相关的运动障碍","authors":"Austeja Baleviciute, Lily Keane","doi":"10.1038/s41577-024-00997-8","DOIUrl":null,"url":null,"abstract":"A preprint by Kim et al. shows that the brain parenchyma can be seeded with age with clonal haematopoiesis-derived monocytes that drive neuropathology.","PeriodicalId":19049,"journal":{"name":"Nature Reviews Immunology","volume":" ","pages":"160-160"},"PeriodicalIF":67.7000,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clonal haematopoiesis-associated, age-related motor deficits caused by monocyte-derived microglia\",\"authors\":\"Austeja Baleviciute, Lily Keane\",\"doi\":\"10.1038/s41577-024-00997-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A preprint by Kim et al. shows that the brain parenchyma can be seeded with age with clonal haematopoiesis-derived monocytes that drive neuropathology.\",\"PeriodicalId\":19049,\"journal\":{\"name\":\"Nature Reviews Immunology\",\"volume\":\" \",\"pages\":\"160-160\"},\"PeriodicalIF\":67.7000,\"publicationDate\":\"2024-01-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature Reviews Immunology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.nature.com/articles/s41577-024-00997-8\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Immunology","FirstCategoryId":"3","ListUrlMain":"https://www.nature.com/articles/s41577-024-00997-8","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
Clonal haematopoiesis-associated, age-related motor deficits caused by monocyte-derived microglia
A preprint by Kim et al. shows that the brain parenchyma can be seeded with age with clonal haematopoiesis-derived monocytes that drive neuropathology.
期刊介绍：
Nature Reviews Immunology is a journal that provides comprehensive coverage of all areas of immunology, including fundamental mechanisms and applied aspects. It has two international standard serial numbers (ISSN): 1474-1733 for print and 1474-1741 for online. In addition to review articles, the journal also features recent developments and new primary papers in the field, as well as reflections on influential people, papers, and events in the development of immunology. The subjects covered by Nature Reviews Immunology include allergy and asthma, autoimmunity, antigen processing and presentation, apoptosis and cell death, chemokines and chemokine receptors, cytokines and cytokine receptors, development and function of cells of the immune system, haematopoiesis, infection and immunity, immunotherapy, innate immunity, mucosal immunology and the microbiota, regulation of the immune response, signalling in the immune system, transplantation, tumour immunology and immunotherapy, and vaccine development.
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