牛结核病随疫苗接种和污染环境演变的分数阶模型

IF 1.2 Q2 MATHEMATICS, APPLIED Journal of Applied Mathematics Pub Date : 2024-01-24 DOI:10.1155/2024/6934895
Boubacar Diallo, J. Okelo, Shaibu Osman, Simon Karanja, N. S. Aguegboh
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引用次数: 0

摘要

牛结核病(bTB)是一种人畜共患病,通常通过吸入气溶胶、饮用未经消毒的牛奶和食用生肉传播。我们使用具有卡普托意义的分数阶模型来研究牛结核病在人类和动物种群中的传播演化,包括人类的疫苗区。我们推导并获得了确定疾病状态的阈值量 R0。我们建立了保证均衡渐近稳定性的条件(局部和全局)。我们进行了敏感性分析,以确定影响结核病动态的因素。研究表明,结核病的人兽传播率和环境污染以及结核病在动物间的传播率都会影响结核病的传播。然而,随着疫苗接种率的提高和食用受污染环境产品(如肉类、牛奶和其他乳制品)的人数减少,该疾病在人类中的发病率也会降低。为了控制牛结核病,建议实施信息计划、监测环境、治疗感染者、为受污染的动物接种疫苗并隔离受污染的动物。通过数值实验证明了所发现的理论结果的实用性。
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Fractional-Order Model for Evolution of Bovine Tuberculosis with Vaccination and Contaminated Environment
Bovine tuberculosis (bTB) is a zoonotic disease that is commonly transmitted via inhaling aerosols, drinking unpasteurized milk, and eating raw meat. We use a fractional-order model with the Caputo sense to examine the evolution of bovine tuberculosis transmission in human and animal populations, including a vaccine compartment for humans. We derived and obtained the threshold quantity R0 to ascertain the illness state. We established conditions guaranteeing the asymptotic stability of the equilibria (locally and globally). Sensitivity analysis was conducted to identify the factors that govern the dynamics of tuberculosis. The study demonstrates that the rate of human-to-animal transmission of tuberculosis and environmental pollution and the rate of bTB transmission between animals all affect tuberculosis transmission. However, as vaccination rates increase and fewer individuals consume contaminated environment products (such as meat, milk, and other dairy products), the disease becomes less common in humans. To manage bovine TB, it is advised that information programmes be implemented, the environment be monitored, infected persons be treated, contaminated animals be vaccinated, and contaminated animals be quarantined. The usefulness of the discovered theoretical results is demonstrated through numerical experiments.
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来源期刊
Journal of Applied Mathematics
Journal of Applied Mathematics MATHEMATICS, APPLIED-
CiteScore
2.70
自引率
0.00%
发文量
58
审稿时长
3.2 months
期刊介绍: Journal of Applied Mathematics is a refereed journal devoted to the publication of original research papers and review articles in all areas of applied, computational, and industrial mathematics.
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