Differentiation of Restless Genital Syndrome from Persistent Genital Arousal Disorder: A Case Report

Persistent genital arousal disorder (PGAD) presents with a constant unwelcome sensation of genital arousal. Moreover, restless genital syndrome (RGS) is one of the restless leg syndrome (RLS) variants. We aimed to clarify the differences between clinical diagnoses of these two similar conditions. Assessing the circadian pattern of symptoms, the simultaneous presence of RLS and restless bladder syndrome, exacerbation of symptoms with caffeine use, healing with magnesium use, and familial history of RLS helped us with the differentiation between PGAD and RGS. We propose to rule out the diagnosis of RGS in all patients with PGAD symptoms.