纳米医学作为一种更好的治疗方法:概述

Arnab Das, Srijita Chakrabarti
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引用次数: 0

摘要

纳米技术和纳米医学领域经历了一场革命。自 1980 年以来,获得授权的纳米药物显著增加。除了作为治疗剂外,它们还作为载体将各种活性药物输送到目标器官。纳米医学的最终目标一直是产生能够改进当前疗法的转化技术。纳米晶体、纳米管、脂质体、外泌体、固体脂质纳米颗粒、聚合物纳米颗粒以及金属和磁性纳米颗粒都是目前市场上和正在研究中的纳米结构的例子。制备这些纳米材料需要考虑许多困难。其中只有少数纳米材料在通过所有必要的毒理学和伦理学评估后,成功地获得了市场许可,使用户能够负担得起,同时也使投资者有利可图。癌症、中枢神经系统(CNS)疾病和心血管系统(CVS)疾病是纳米技术应用于医学的主要目标。因此,这篇综述文章重点总结了几种基于纳米的给药系统,包括它们在不同治疗领域的局限性和前景。
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Nanomedicine as a Better Therapeutic Approach: An Overview
The fields of nanotechnology and nanomedicine have undergone a revolution. There has been a striking rise in authorized nanomedicines since 1980. Apart from functioning as therapeutic agents, they also act as carriers for delivering various active pharmaceuticals to target organs. The ultimate goal of nanomedicine has always been the generation of translational technologies that can improve current therapies. Nanocrystals, nanotubes, liposomes, exosomes, solid lipid nanoparticles, polymeric nanoparticles, and metallic and magnetic nanoparticles are examples of nanostructures that are now in the market as well as in ongoing research. The preparation of these nanomaterials requires consideration of a number of difficulties. Only a few of these nano-materials were successful in obtaining marketing permission after passing all required toxicological and ethical evaluations and making them affordable to users and, at the same time, profitable to investors. Cancer, Central nervous system (CNS) diseases, and Cardiovascular (CVS) diseases represented the primary targets of nanotechnology applied to medicine. Therefore, this review article is focused on providing a summary of several nano-based delivery systems, including their limitations and prospects in different therapeutic fields.
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来源期刊
Current Nanomedicine
Current Nanomedicine Medicine-Medicine (miscellaneous)
CiteScore
2.00
自引率
0.00%
发文量
15
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