洛夫勒心内膜炎临床病例

S. S. Yashin, Yuliya Yunusova, M. N. Chadayeva
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摘要

嗜酸性粒细胞性心内膜炎是由嗜酸性粒细胞直接浸润心脏组织并引发特异性炎症引起的。该病的主要致病因素是外周血中嗜酸性粒细胞水平显著升高。洛夫勒综合征可由特发性嗜酸性粒细胞过多综合征、过敏性疾病、寄生虫感染、自身免疫过程、癌症等因素和病理条件引起。本文介绍了一例 84 岁患者的洛夫勒综合征临床病例,该患者伴有心、肺、肝、肾和胰腺病变。文章讨论了由于该综合征的临床表现和病程征兆各不相同而造成的鉴别诊断困难。及时诊断这种病症可以防止严重并发症的迅速发展,并进行适当的治疗,这将大大延长洛夫勒综合征患者的生命。然而,在出现非特异性症状时,医生可能很难诊断出这种疾病。
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Clinical case of Loeffler’s endomyocarditis
Eosinophilic endomyocarditis is caused by direct infiltration of heart tissue by eosinophils with the development of specific inflammation. The main etiological factor of the disease is a significant increase in the level of eosinophils in peripheral blood. Loeffler syndrome can be caused by such factors and pathological conditions as idiopathic hypereosinophilic syndrome, allergic diseases, parasitic infections, autoimmune processes, cancer. A clinical case of Loeffler syndrome in an 84-year-old patient with heart, lung, liver, kidney and pancreatic lesions is presented. Difficulties of differential diagnostics of this syndrome because of individual clinical picture and signs of the course are discussed in the article. Timely diagnosis of such a condition will prevent the rapid development of severe complications and carry out appropriate therapy, which will significantly prolong the life of patients with Loeffler syndrome. However, in the presence of nonspecific symptoms, the diagnosis of this disease may be diagnostically difficult for the physician.
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