孟加拉国 Covid-19 患者的基线特征和治疗结果

Anm Shamsul Islam, Md Golam Abbas, Md Nazmul Hassan Refat, KM Baizid Amin, M. M. Hasan, Mosfika Rahman
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摘要

背景:冠状病毒病-2019(COVID-19)是由严重急性呼吸系统综合征冠状病毒2(SARS-CoV-2)引起的疾病。世卫组织于 2020 年 2 月 11 日发布新闻稿,宣布该疾病为大流行病。经证实,该病毒已于 2020 年 3 月传播到孟加拉国。为了防治这种大流行病,必须确定 COVID-19 患者在孟加拉国的基本特征。研究方法这项横断面研究是在国家预防和社会医学研究所(NIPSOM)实验室通过反转录酶聚合酶链反应(RT-PCR)检测确诊的 1016 名 COVID-19 患者中进行的。研究在 2020 年 3 月至 6 月期间进行,通过电话使用预先测试过的半结构化问卷收集参与者的数据。结果:研究显示,在 1016 名受访者中,64.1% 为男性,其余 35.9%为女性。近一半的受访者(46.5%)年龄在 19-39 岁之间。72.6%的受访者已婚,39.6%的受访者为研究生及以上学历。超过三分之二的受访者(69.3%)居住在城市地区,72.7%来自核心家庭。在检测结果呈阳性的第 14 天或以后,RT-PCR 检测-1 发现 12.5%呈阳性,而在检测结果呈阳性的第 28 天或以后,RT-PCR 检测-2 发现仅有 3.3%呈阳性。另一方面,未进行 RT-PCR 测试-1 的占 11.6%,未进行 RT-PCR 测试-2 的占 41.8%。在检测结果呈阳性的第 14 天或之后,62.1% 的患者继续接受治疗,而在第 28 天或之后,仅有 3.5%的患者因病毒相关并发症而继续接受治疗。结论孟加拉确诊 COVID-19 阳性病例的连续检测患者的基线特征、严重程度和结果。这些信息应在全国范围内传播,以提高政策制定者的意识,并采取必要措施防止科晕病毒在孟加拉国传播。JOPSOM 2021; 41(2):36-42
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Baseline Characteristics And Outcome Of Covid-19 Patients In Bangladesh
Background: Coronavirus disease-2019 (COVID-19) is the disease caused by Severe Acute Respiratory Syndrome Corona virus 2 (SARS-CoV-2). The disease was declared as a pandemic by WHO in a press release on 11 February 2020. The virus was confirmed to have spread to Bangladesh in March 2020. To combat this pandemic disease, baseline characteristics of the COVID-19 patients are essential to be identified in the context of Bangladesh. Methods: The cross-sectional study was conducted among 1016 COVID-19 patients diagnosed by Reversed Transcriptase-Polymerase Chain Reaction (RT-PCR) assay at the National Institute of Preventive and Social Medicine (NIPSOM) laboratory. The study was conducted during the period from March to June 2020, Data were collected form the participants, who were selected conveniently and were interviewed by using a pre-tested semi-structured questionnaire over telephone. Results: The study revealed that among 1016 respondents, 64.1% were male and the rest 35.9% were female. Almost half of the respondents (46.5%) were aged 19-39 years. Among the respondents, 72.6% were married and 39.6% were graduated and above. More than two-thirds (69.3%) of the respondents lived in urban area and 72.7% were from nuclear family. On the fourteenth (14th) day or onwards of being positive, RT–PCR Test-1 found 12.5% positive and on twenty-eighth (28th) day or onwards RT–PCR Test-2 found positive only 3.3%. On the other hand, RT–PCR Test-1 was not done by 11.6% and RT–PCR Test-2 by 41.8%. While on the fourteenth (14th) day or onwards of being positive, 62.1% patients were continuing treatment and on the twenty-eighth (28th) day or onwards only 3.5% patients were continuing treatment due to covid related complications. Conclusion: Baseline characteristics, severity and outcomes of sequentially tested patients with confirmed COVID-19 positive cases in Bangladesh. Such information should be disseminated across the country to raise awareness and initiate necessary measures by the policy makers to prevent spread of corona virus in Bangladesh. JOPSOM 2021; 41(2):36-42
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