S. Quenby, Katie Booth, Louise Hiller, A. Coomarasamy, Paulien G. de Jong, Eva N. Hamulyák, L. Scheres, T. V. van Haaps, L. Ewington, Shreeya Tewary, M. Goddijn, Saskia Middeldorp
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Heparin for Women With Recurrent Miscarriage and Inherited Thrombophilia (ALIFE2): An International Open-Label, Randomised Controlled Trial
(Abstracted from Lancet 2023;402:54–61)
Inherited thrombophilia is implicated as a cause of recurrent pregnancy loss, defined as the loss of 2 or more pregnancies. Heparin is the standard treatment for acquired thrombophilia but is not recommended in cases of recurrent pregnancy loss and inherited thrombophilia.