2 型糖尿病患者的超低卡路里饮食和完全饮食替代:我们现在在哪里?

Roy Taylor
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引用次数: 0

摘要

2 型糖尿病的病因是肝脏中脂肪过多,以及肝脏输出过多脂肪抑制了 beta 细胞的功能,这一认识简化了对 2 型糖尿病的管理。这些因素都可以通过大幅减肥来扭转,从而在确诊后的最初几年使病情得到缓解,或至少大大降低心血管风险,并改善所有人的血糖控制。通过任何方式减轻体重都是成功的,但最容易实现的方法是迅速采取行动,采用低热量或极低热量饮食,每天约 800 千卡,然后持续适度控制饮食习惯。口服降糖药和一种降压药可在减肥饮食的第一天停用,因此适当停药非常重要。
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Very low calorie diets and total diet replacement in type 2 diabetes: where are we now?

Management of type 2 diabetes has now been simplified by the understanding that the condition is caused by excess fat in the liver together with suppression of beta cell function by the associated excess liver export of fat. These factors can be reversed by substantial weight loss leading to remission in the early years after diagnosis, or at least major decrease in cardiovascular risks and improvement in glucose control for all. Weight loss by any means is successful, but it is most easily achieved by rapid action using a low or very low calorie diet of around 800 kcal/day followed by sustained modest restraint of dietary habits. Oral hypoglycaemic agents and one antihypertensive drug can be withdrawn on day 1 of the weight loss diet, raising the importance of appropriate deprescribing.

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Drug and Therapeutics Bulletin
Drug and Therapeutics Bulletin Medicine-Pharmacology (medical)
CiteScore
0.80
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发文量
69
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