母体高血糖时胎儿的新陈代谢状况。

IF 11.4 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM Trends in Endocrinology and Metabolism Pub Date : 2024-04-01 Epub Date: 2024-02-09 DOI:10.1016/j.tem.2024.01.012
Miranda E Kelly, Thomas F Martinez, Cholsoon Jang
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引用次数: 0

摘要

母体高血糖会导致胎儿发育异常;然而,人们对高血糖如何影响胎儿代谢却知之甚少。Perez-Ramirez 及其同事最近提供了一个从正常怀孕小鼠和糖尿病怀孕小鼠中分离出来的胎儿器官的综合代谢图谱,确定了新的代谢物以及母体高血糖在整个妊娠中晚期对组织葡萄糖利用的改变。
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The landscape of fetus metabolism in maternal hyperglycemia.

Maternal hyperglycemia contributes to abnormal fetal development; yet, how it affects fetal metabolism is poorly understood. Perez-Ramirez and colleagues recently provided a comprehensive metabolic atlas of fetal organs isolated from normal and diabetic pregnant mice, identifying novel metabolites and alterations in tissue glucose utilization throughout mid-to-late gestation by maternal hyperglycemia.

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来源期刊
Trends in Endocrinology and Metabolism
Trends in Endocrinology and Metabolism 医学-内分泌学与代谢
CiteScore
20.10
自引率
0.00%
发文量
98
审稿时长
82 days
期刊介绍: Trends in Endocrinology and Metabolism (TEM) stands as a premier Reviews journal in the realms of metabolism and endocrinology. Our commitment is reflected in the publication of refined, concise, and highly impactful articles that delve into cutting-edge topics, encompassing basic, translational, and clinical aspects. From state-of-the-art treatments for endocrine diseases to groundbreaking developments in molecular biology, TEM provides comprehensive coverage. Explore recent advancements in diabetes, endocrine diseases, obesity, neuroendocrinology, immunometabolism, molecular and cellular biology, and a myriad of other areas through our journal. TEM serves as an invaluable resource for researchers, clinicians, lecturers, teachers, and students. Each monthly issue is anchored by Reviews and Opinion articles, with Reviews meticulously chronicling recent and significant developments, often contributed by leading researchers in specific fields. Opinion articles foster debate and hypotheses. Our shorter pieces include Science & Society, shedding light on issues at the intersection of science, society, and policy; Spotlights, which focus on exciting recent developments in the literature, and single-point hypotheses as Forum articles. We wholeheartedly welcome and encourage responses to previously published TEM content in the form of Letters.
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