[乙葡醛酸乙酯在乙醇消费诊断中的使用问题]。

A A Khalikov, V N Korotun, I Yu Smirnova, K O Kuznetsov, A R Galimov, L R Iskuzhina
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引用次数: 0

摘要

近年来,不同生物对象中乙基葡萄糖醛酸(EtG)的定量测定已被定位为无条件饮酒最可靠的生物标志物之一。本研究旨在总结目前国内外文献中使用 EtG 进行酒精消耗量检测的分析方法,并对 EtG 结果的可重复性和研究解释中可能出现的误差进行示意性概述,这些误差可能会限制其在法医实践中的使用。主要目的是提高 EtG 作为乙醇消耗量标志物的可靠性和有效性。
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[Problems of ethyl glucuronide use in ethanol consumption diagnosis].

Quantitative determination of ethyl glucuronide (EtG) in different biological objects in recent years has been positioned as one of the most reliable biomarkers of unconditional alcohol consumption. The aim of the study is to summarize the analytical methods of alcohol consumption testing with the use of EtG currently available in domestic and foreign literature and to present a schematic overview of possible errors in reproducibility and interpretation of research on EtG results, which may limit their use in forensic medical practice. The main objective is to increase the reliability and validity of EtG as a marker of ethanol consumption.

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来源期刊
Sudebno-Meditsinskaya Ekspertisa
Sudebno-Meditsinskaya Ekspertisa Medicine-Pathology and Forensic Medicine
CiteScore
0.60
自引率
0.00%
发文量
70
期刊介绍: The journal is concerned with the theory and practice of forensic medicine - the problems of thanatology, traumatology, toxicology, serology, forensic obstetrics, forensic dentistry, forensic psychiatry, forensic chemistry, physicotechnical methods of investigation, history of forensic medicine and some problems of criminology and legal laws related to forensic medicine. It publishes original studies by Russian authors, casuistry surveys, abstracts and reviews of Russian and foreign literature, scientific information, reports on scientific conferences.
期刊最新文献
[Criminal-legal assessment of causality in violations of medical care committed at different stages]. [Determination of formation age of acute traumatic intracranial subdural hematomas using computed tomography]. [Expertise of anthropometric indicators of children and adolescents of the Nizhny Novgorod Region in 1944/45-1959/60-2019/22]. [About compliance with the real conditions of adopted forensic models of the victim's fall from standing position on the back]. [Method of linear calibration function control according to GOST R ISO 11095-2007 for measuring the mass concentration of ethanol].
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