需要使用血管加压素的脓毒性休克重症患者的肠内营养:病例报告。

Clinical nutrition research Pub Date : 2024-01-26 eCollection Date: 2024-01-01 DOI:10.7762/cnr.2024.13.1.1
Hee Young Kim, Min Young Noh, Jisun Lee
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引用次数: 0

摘要

重症患者的营养支持是治疗的一个重要方面。尤其是肠内营养(EN)的益处已得到广泛认可,各种指南都建议危重病人在 48 小时内尽早进行肠内营养。然而,对于需要使用血管加压剂的脓毒性休克重症患者,肠内营养仍存在争议。因此,本病例报告旨在为需要血管加压的脓毒性休克患者提供安全有效的营养支持的基本数据。一名 62 岁的男性患者因颈部深部感染和纵隔炎恶化为脓毒症而被送入重症监护室。由于呼吸性酸中毒和精神状态恶化,插管后开始机械通气,严重低血压需要使用去甲肾上腺素。由于血流动力学不稳定,患者一直处于无呼吸状态。随后,在去甲肾上腺素剂量减少的同时开始营养喂养,并逐渐增加,到开始肠内喂养的第 7 天,通过 EN 达到能量需求的 75%。虽然在增加 EN 的阶段出现了进食不耐受的迹象,但调整 EN 的速度后问题得到了解决。本病例报告展示了需要使用血管加压剂的脓毒性休克患者逐步坚持肠内喂养的过程,所观察到的进展与现有的研究和指南相对一致。今后,我们认为有必要对需要使用血管加压剂的脓毒性休克重症患者进行进一步的病例报告和持续研究,以便为其提供安全有效的营养支持。
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Enteral Nutrition in Critically Ill Patient With Septic Shock Requiring Vasopressor: Case Report.

Nutritional support in critically ill patients is an essential aspect of treatment. In particular, the benefits of enteral nutrition (EN) are well recognized, and various guidelines recommend early EN within 48 hours in critically ill patients. However, there is still controversy regarding EN in critically ill patients with septic shock requiring vasopressors. Therefore, this case report aims to provide basic data for the safe and effective nutritional support in septic shock patients who require vasopressors. A 62-year-old male patient was admitted to the intensive care unit with a deep neck infection and mediastinitis that progressed to a septic condition. Mechanical ventilation was initiated after intubation due to progression of respiratory acidosis and deterioration of mental status, and severe hypotension required the initiation of norepinephrine. Due to hemodynamic instability, the patient was kept nil per os. Subsequently, trophic feeding was initiated at the time of norepinephrine dose tapering and was gradually increased to achieve 75% of the energy requirement through EN by the 7th day of enteral feeding initiation. Although there were signs of feeding intolerance during the increasing phase of EN, adjusting the rate of EN resolved the issue. This case report demonstrates the gradual progression and adherence to EN in septic shock patient requiring vasopressors, and the progression observed was relatively consistent with existing studies and guidelines. In the future, further case reports and continuous research will be deemed necessary for safe and effective nutritional support in critically ill patients with septic shock requiring vasopressors.

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