监测接受药物辅助治疗患者体内的丁丙诺啡

Q3 Medicine Journal of opioid management Pub Date : 2024-02-08 DOI:10.5055/jom.0844

Amadeo Pesce, Katie Bollman, Kevin Krock, A. Cua, Keith Tran, Richard Thomas

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引用次数: 0

摘要

背景：丁丙诺啡用于阿片类药物依赖的药物辅助治疗。目的：监测服药依从性包括检测尿液或口服液中的药物或其代谢物。方法：使用液相色谱串联质谱仪检测定量结果，确定药物及其代谢物的排泄模式。结果丁丙诺啡和去甲丁丙诺啡的频率分布曲线描述了服用这种药物的患者的预期药物浓度。结论：尿液和口服液药物检测可用于监测此类人群的服药依从性。

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Monitoring buprenorphine in patients on medication-assisted treatment

Background: Buprenorphine is used for medication-assisted treatment of opioid dependence. Purpose: Monitoring of medication adherence involves testing of urine or oral fluid for the drug or its metabolite. Methods: Quantitative results using liquid chromatography tandem mass spectrometer testing defined the excretion pattern of the drug and its metabolites. Results: Frequency distribution curves of buprenorphine and norbuprenorphine describe the expected drug concentrations of patients on this medication. Conclusion: Urine and oral fluid drug testing can be used to monitor adherence in this population.

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来源期刊

Journal of opioid management Medicine-Anesthesiology and Pain Medicine

CiteScore

1.00

自引率

0.00%

发文量

期刊介绍： The Journal of Opioid Management deals with all aspects of opioids. From basic science, pre-clinical, clinical, abuse, compliance and addiction medicine, the journal provides and unbiased forum for researchers and clinicians to explore and manage the complexities of opioid prescription.