{"title":"基于育种值 BLUP 的截断选择反应预测及其预测精度","authors":"Masahiro Satoh","doi":"10.1111/asj.13928","DOIUrl":null,"url":null,"abstract":"<p>Three methods of predicting the response to truncated selection based on BLUP of breeding values (BVs) were compared under conditions in which the phenotypic values for the progenies of selected animals were not available. The following methods were used to predict the response to selection: (1) based on the mean of estimated breeding values (EBV) in the candidate population for selection (<math>\n <semantics>\n <mrow>\n <mo>∆</mo>\n <msub>\n <mi>g</mi>\n <mn>1</mn>\n </msub>\n </mrow>\n <annotation>$$ \\Delta {\\mathrm{g}}_1 $$</annotation>\n </semantics></math>), (2) based on the variance of EBV in the candidate population for selection (<math>\n <semantics>\n <mrow>\n <mo>∆</mo>\n <msub>\n <mi>g</mi>\n <mn>2</mn>\n </msub>\n </mrow>\n <annotation>$$ \\Delta {\\mathrm{g}}_2 $$</annotation>\n </semantics></math>), and (3) based on diagonal elements of the inverse matrix on the left-hand side of the mixed model equation (<math>\n <semantics>\n <mrow>\n <mo>∆</mo>\n <msub>\n <mi>g</mi>\n <mn>3</mn>\n </msub>\n </mrow>\n <annotation>$$ \\Delta {\\mathrm{g}}_3 $$</annotation>\n </semantics></math>). The deviation of the average BV of the selected animals from the average BV of the candidate population for selection was taken as the true response to selection. The pedigree information and phenotypic values used for comparison were generated by Monte Carlo computer simulation. The results showed that <math>\n <semantics>\n <mrow>\n <mo>∆</mo>\n <msub>\n <mi>g</mi>\n <mn>1</mn>\n </msub>\n </mrow>\n <annotation>$$ \\Delta {\\mathrm{g}}_1 $$</annotation>\n </semantics></math> had the smallest absolute mean error and <math>\n <semantics>\n <mrow>\n <mo>∆</mo>\n <msub>\n <mi>g</mi>\n <mn>2</mn>\n </msub>\n </mrow>\n <annotation>$$ \\Delta {\\mathrm{g}}_2 $$</annotation>\n </semantics></math> had the smallest root-mean-square error. We concluded that it is desirable to use <math>\n <semantics>\n <mrow>\n <mo>∆</mo>\n <msub>\n <mi>g</mi>\n <mn>1</mn>\n </msub>\n </mrow>\n <annotation>$$ \\Delta {\\mathrm{g}}_1 $$</annotation>\n </semantics></math> or <math>\n <semantics>\n <mrow>\n <mo>∆</mo>\n <msub>\n <mi>g</mi>\n <mn>2</mn>\n </msub>\n </mrow>\n <annotation>$$ \\Delta {\\mathrm{g}}_2 $$</annotation>\n </semantics></math> to predict the response to truncated selection based on BLUP of BVs. However, in the population where selection is ongoing, the prediction accuracy of selection response is likely to be affected by the distortion of the distribution and the Bulmer effect for <math>\n <semantics>\n <mrow>\n <mo>∆</mo>\n <msub>\n <mi>g</mi>\n <mn>2</mn>\n </msub>\n </mrow>\n <annotation>$$ \\Delta {\\mathrm{g}}_2 $$</annotation>\n </semantics></math>.</p>","PeriodicalId":7890,"journal":{"name":"Animal Science Journal","volume":null,"pages":null},"PeriodicalIF":1.7000,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/asj.13928","citationCount":"0","resultStr":"{\"title\":\"Prediction of response to truncated selection based on BLUP of breeding values and its prediction accuracy\",\"authors\":\"Masahiro Satoh\",\"doi\":\"10.1111/asj.13928\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Three methods of predicting the response to truncated selection based on BLUP of breeding values (BVs) were compared under conditions in which the phenotypic values for the progenies of selected animals were not available. The following methods were used to predict the response to selection: (1) based on the mean of estimated breeding values (EBV) in the candidate population for selection (<math>\\n <semantics>\\n <mrow>\\n <mo>∆</mo>\\n <msub>\\n <mi>g</mi>\\n <mn>1</mn>\\n </msub>\\n </mrow>\\n <annotation>$$ \\\\Delta {\\\\mathrm{g}}_1 $$</annotation>\\n </semantics></math>), (2) based on the variance of EBV in the candidate population for selection (<math>\\n <semantics>\\n <mrow>\\n <mo>∆</mo>\\n <msub>\\n <mi>g</mi>\\n <mn>2</mn>\\n </msub>\\n </mrow>\\n <annotation>$$ \\\\Delta {\\\\mathrm{g}}_2 $$</annotation>\\n </semantics></math>), and (3) based on diagonal elements of the inverse matrix on the left-hand side of the mixed model equation (<math>\\n <semantics>\\n <mrow>\\n <mo>∆</mo>\\n <msub>\\n <mi>g</mi>\\n <mn>3</mn>\\n </msub>\\n </mrow>\\n <annotation>$$ \\\\Delta {\\\\mathrm{g}}_3 $$</annotation>\\n </semantics></math>). The deviation of the average BV of the selected animals from the average BV of the candidate population for selection was taken as the true response to selection. The pedigree information and phenotypic values used for comparison were generated by Monte Carlo computer simulation. The results showed that <math>\\n <semantics>\\n <mrow>\\n <mo>∆</mo>\\n <msub>\\n <mi>g</mi>\\n <mn>1</mn>\\n </msub>\\n </mrow>\\n <annotation>$$ \\\\Delta {\\\\mathrm{g}}_1 $$</annotation>\\n </semantics></math> had the smallest absolute mean error and <math>\\n <semantics>\\n <mrow>\\n <mo>∆</mo>\\n <msub>\\n <mi>g</mi>\\n <mn>2</mn>\\n </msub>\\n </mrow>\\n <annotation>$$ \\\\Delta {\\\\mathrm{g}}_2 $$</annotation>\\n </semantics></math> had the smallest root-mean-square error. We concluded that it is desirable to use <math>\\n <semantics>\\n <mrow>\\n <mo>∆</mo>\\n <msub>\\n <mi>g</mi>\\n <mn>1</mn>\\n </msub>\\n </mrow>\\n <annotation>$$ \\\\Delta {\\\\mathrm{g}}_1 $$</annotation>\\n </semantics></math> or <math>\\n <semantics>\\n <mrow>\\n <mo>∆</mo>\\n <msub>\\n <mi>g</mi>\\n <mn>2</mn>\\n </msub>\\n </mrow>\\n <annotation>$$ \\\\Delta {\\\\mathrm{g}}_2 $$</annotation>\\n </semantics></math> to predict the response to truncated selection based on BLUP of BVs. However, in the population where selection is ongoing, the prediction accuracy of selection response is likely to be affected by the distortion of the distribution and the Bulmer effect for <math>\\n <semantics>\\n <mrow>\\n <mo>∆</mo>\\n <msub>\\n <mi>g</mi>\\n <mn>2</mn>\\n </msub>\\n </mrow>\\n <annotation>$$ \\\\Delta {\\\\mathrm{g}}_2 $$</annotation>\\n </semantics></math>.</p>\",\"PeriodicalId\":7890,\"journal\":{\"name\":\"Animal Science Journal\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2024-02-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1111/asj.13928\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Animal Science Journal\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/asj.13928\",\"RegionNum\":3,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"AGRICULTURE, DAIRY & ANIMAL SCIENCE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Animal Science Journal","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/asj.13928","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"AGRICULTURE, DAIRY & ANIMAL SCIENCE","Score":null,"Total":0}
引用次数: 0
摘要
在无法获得被选动物后代表型值的条件下,比较了基于育种值(BVs)的BLUP预测截断选择反应的三种方法。预测选择反应的方法如下(1) 基于候选选择群体中估计育种值(EBV)的平均值(∆ g 1 $$ \Delta {\mathrm{g}}_1 $$),(2) 基于候选选择群体中 EBV 的方差(∆ g 2 $$ \Delta {\mathrm{g}}_2 $$)、和 (3) 基于混合模型方程左侧逆矩阵的对角元素(∆ g 3 $$ \Delta {\mathrm{g}}_3 $$ )。被选动物的平均 BV 与候选群体平均 BV 的偏差被视为对选择的真实响应。用于比较的血统信息和表型值由蒙特卡罗计算机模拟生成。结果表明,∆ g 1 $$ \Delta {\mathrm{g}}_1 $$ 的绝对平均误差最小,∆ g 2 $$ \Delta {\mathrm{g}}_2 $$ 的均方根误差最小。我们得出结论,使用 ∆ g 1 $ $ (△ {\mathrm{g}}_1 $ $ )或 ∆ g 2 $ $ (△ {\mathrm{g}}_2 $ )来预测基于 BV 的 BLUP 的截断选择反应是可取的。然而,在选择正在进行的群体中,选择响应的预测精度很可能会受到 ∆ g 2 $$ \Delta {\mathrm{g}}_2 $$ 分布失真和 Bulmer 效应的影响。
Prediction of response to truncated selection based on BLUP of breeding values and its prediction accuracy
Three methods of predicting the response to truncated selection based on BLUP of breeding values (BVs) were compared under conditions in which the phenotypic values for the progenies of selected animals were not available. The following methods were used to predict the response to selection: (1) based on the mean of estimated breeding values (EBV) in the candidate population for selection (), (2) based on the variance of EBV in the candidate population for selection (), and (3) based on diagonal elements of the inverse matrix on the left-hand side of the mixed model equation (). The deviation of the average BV of the selected animals from the average BV of the candidate population for selection was taken as the true response to selection. The pedigree information and phenotypic values used for comparison were generated by Monte Carlo computer simulation. The results showed that had the smallest absolute mean error and had the smallest root-mean-square error. We concluded that it is desirable to use or to predict the response to truncated selection based on BLUP of BVs. However, in the population where selection is ongoing, the prediction accuracy of selection response is likely to be affected by the distortion of the distribution and the Bulmer effect for .
期刊介绍:
Animal Science Journal (a continuation of Animal Science and Technology) is the official journal of the Japanese Society of Animal Science (JSAS) and publishes Original Research Articles (full papers and rapid communications) in English in all fields of animal and poultry science: genetics and breeding, genetic engineering, reproduction, embryo manipulation, nutrition, feeds and feeding, physiology, anatomy, environment and behavior, animal products (milk, meat, eggs and their by-products) and their processing, and livestock economics. Animal Science Journal will invite Review Articles in consultations with Editors. Submission to the Journal is open to those who are interested in animal science.