液基细胞学在检测宫颈癌疑似病例方面是一种优于传统巴氏涂片的工具:比较研究

IF 0.4 Q4 BIOLOGY Advances in Human Biology Pub Date : 2024-02-20 DOI:10.4103/aihb.aihb_100_23
Subhashish Das, R. Kalyani, S. Sheela, K. Kamala
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引用次数: 0

摘要

传统细胞学筛查项目(如传统巴氏涂片检查(CPS))已成功减少了宫颈癌的发生,但手动液基细胞学检查(MLBC)和人类乳头瘤病毒检测等更新的检测方法可能会加强筛查工作。 这是一项横断面研究,对 175 份样本进行了 CPS 和 MLBC 检测。液态乳头状瘤病毒检测使用的是细胞刷,细胞刷在防腐液中悬浮并分离,然后用手工方法进行处理。还进行了组织病理学相关性和 HPV DNA 检测。 与 CPS 相比,MLBC 显示出更高的标本充分性、细胞度、清洁背景和细胞分布均匀性。 MLBC的标本充分性、细胞形态学特征和上皮细胞异常检出率均高于CPS。
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Liquid-based Cytology as a Superior Tool Compared to Conventional Pap Smear in Detecting Cervical Cancer in Suspected Cases: A Comparative Study
Screening programs has conventional cytology such as Conventional Pap Smear (CPS) have successfully reduced cervical cancer, but newer tests like Manual Liquid-based cytology (MLBC) and Human Papillomavirus testing might enhance screening. This was a cross sectional study conducted on 175 samples was processed for CPS and MLBC. Cytobrush was used for LBC which was suspended and detached in the preservative fluid and processed by manual method. Histopathological correlation and HPV DNA testing was also done. MLBC showed higher specimen adequately, cellularity, clean background and uniform distribution of cells than CPS. MLBC showed improved specimen adequately, better cytomorphological features and higher detection of epithelial cell abnormality.
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