开放性胫骨中轴骨折皮瓣覆盖延迟会增加并发症:一项回顾性研究

A. Mahmoud, Jarrod Younger, Emily Morris, Matthew Hope
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摘要

背景:这项回顾性研究旨在评估在开放性胫骨中段骨折中延迟皮瓣覆盖是否会导致更高的感染率。研究方法从2012年至2020年期间的三级创伤数据库中回顾性招募患者。纳入的患者年龄在18岁以上,胫骨开放性骨折需要皮瓣覆盖,随访至少6个月。收集的并发症包括深部感染、无菌性不愈合、皮瓣失败和翻修手术。结果对 A 组(18 人)和 B 组(37 人)进行了分析。A组深度感染率为6%,B组为38%,差异显著,χ2(1,N = 55)= 6.4,P = 0.01。A组的翻修手术率为17%,B组为54%,差异显著,χ2(1,N = 55)= 7,P = 0.008。二元逻辑回归显示,B 组发生深度感染的几率是 A 组的 10 倍(95% 置信区间 1.2-83, p = 0.034)。结论开放性胫骨骨折软组织覆盖延迟一周以上会增加深部感染和翻修手术的风险。
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A delay in flap coverage of open midshaft tibia fractures increases complications: A retrospective study
Background: This retrospective study aimed to assess whether delaying flap coverage in open midshaft tibia fractures leads to higher infection rates. Methods: Patients were recruited retrospectively from a tertiary trauma database between 2012 and 2020. Patients included were over 18-years old and had an open tibia fracture that required flap coverage with at least 6 months follow-up. The collected complications were deep infections, aseptic non-union, flap failure and revision surgery. Results: Group-A ( n = 18) and Group-B ( n = 37) were analysed. Deep infections rate was 6% in Group-A and 38% in Group-B which was significantly different, χ2(1, N = 55) = 6.4, p = 0.01. The rate of revision surgery was 17% in Group-A and 54% in Group-B and was significant, χ2(1, N = 55) = 7, p = 0.008. Binary logistic regression showed that Group-B were 10 times more likely to develop a deep infection (95% confidence interval 1.2–83, p = 0.034). Conclusion: Delaying soft tissue coverage of open tibia fractures for over a week increases the risk of deep infection and revision surgery.
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