肺癌手术的进展:分段切除术在早期治疗中的作用。

Luca Bertolaccini, Monica Casiraghi, Clarissa Uslenghi, Cristina Diotti, Antonio Mazzella, Giovanni Caffarena, Lorenzo Spaggiari
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引用次数: 0

摘要

导言:随着早期非小细胞肺癌(NSCLC)外科干预方法的不断发展,有必要重新评估传统的肺叶切除术与新出现的肺叶下切除术的黄金标准,这促使我们撰写这篇重要的叙述性综述:本综述涵盖最近的随机对照试验,特别是 JCOG0802/WJOG4607L 和 CALGB140503,这些试验比较了早期 NSCLC 的肺叶切除术和叶下切除术,重点关注肿瘤大小和复发率。报告还讨论了个体化决策的重要性、未来的研究途径以及肺癌手术的技术进步:专家观点:在这一快速发展的领域,对于肿瘤小于2厘米的早期NSCLC患者,叶下切除术已成为肺叶切除术的可行替代方案,这就要求对患者进行精确选择,并不断推进技术进步,以优化治疗效果。
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Advances in lung cancer surgery: the role of segmentectomy in early-stage management.

Introduction: The evolving landscape of surgical interventions for early-stage non-small cell lung cancer (NSCLC) necessitates a reassessment of the traditional gold standard of lobectomy versus emerging sublobar resections, prompting this critical narrative review.

Areas covered: This review encompasses recent randomized controlled trials, notably JCOG0802/WJOG4607L and CALGB140503, comparing lobectomy and sublobar resections for early-stage NSCLC, focusing on tumor size and recurrence rates. It also discusses the importance of individualized decision-making, future research avenues, and technological advancements in lung cancer surgery.

Expert opinion: In this rapidly evolving field, sublobar resections emerge as a viable alternative to lobectomy for tumors smaller than 2 cm in early-stage NSCLC, necessitating precise patient selection and ongoing technological advancements to optimize outcomes.

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