邻里守望：与 IP3 受体对话的双孔-2 通道

IF 4.3 2区生物学 Q2 CELL BIOLOGY Cell calcium Pub Date : 2024-03-05 DOI:10.1016/j.ceca.2024.102868

David N Criddle, Alexei V Tepikin

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引用次数: 0

摘要

最近，Y. Yuan 及其同事对溶酶体双孔通道 2（TPC2）和位于内质网的 IP3 受体（IP3Rs）之间的功能关系进行了深入研究 [1]。这项研究的结果表明，这些通道和受体之间存在功能耦合。该研究还描述了一些有趣的新现象，这些现象可能预示着另一种耦合机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Neighbourhood Watch: Two-pore-2 channels talking to IP3 receptors

The recent elegant study by Y. Yuan and colleagues examined functional relationships between the lysosomal two-pore channels 2 (TPC2) and IP3 receptors (IP3Rs) located in the endoplasmic reticulum [1]. The findings of this study suggest functional coupling of these channels and receptors. The study also describes interesting novel phenomena, which may indicate an additional coupling mechanism.

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来源期刊

Cell calcium 生物-细胞生物学

CiteScore

8.70

自引率

5.00%

发文量

115

审稿时长

35 days

期刊介绍： Cell Calcium covers the field of calcium metabolism and signalling in living systems, from aspects including inorganic chemistry, physiology, molecular biology and pathology. Topic themes include: Roles of calcium in regulating cellular events such as apoptosis, necrosis and organelle remodelling Influence of calcium regulation in affecting health and disease outcomes