根据粘弹性测试(VET)更新急性创伤出血和创伤诱发凝血病(TIC)的病理生理学和治疗方法。

IF 1.9 Q2 EMERGENCY MEDICINE Clinical and Experimental Emergency Medicine Pub Date : 2024-09-01 Epub Date: 2024-03-15 DOI:10.15441/ceem.24.202
Marc Maegele
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引用次数: 0

摘要

无法控制的出血和创伤诱发凝血病(TIC)仍然是造成创伤后可预防死亡的两个主要原因。早期控制出血源以及快速检测、鉴定和处理 TIC 与改善预后有关。然而,最近的调查证实,即使在先进的创伤中心,急性创伤出血和 TIC 的临床诊断和管理也存在很大的差异。此外,传统的凝血检测方法虽然在创伤出血患者的早期评估中仍被频繁使用,但也有其局限性。这篇叙事性综述强调了快速护理点粘弹性测试(VET)在早期诊断和对 TIC 出血创伤患者进行个体化目标导向治疗方面的临床价值。
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Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testing.

Uncontrolled hemorrhage and trauma-induced coagulopathy (TIC) are the two predominant causes of preventable death after trauma. Early control of bleeding sources and rapid detection, characterization and management of TIC have been associated with improved outcomes. However, recent surveys confirm vast heterogeneity in the clinical diagnosis and management of hemorrhage and TIC from acute trauma, even in advanced trauma centers. In addition, conventional coagulation assays, although still used frequently during the early assessment of bleeding trauma patients, have their limitations. This narrative review highlights the clinical value of rapid point-of-care viscoelastic testing for the early diagnosis and individualized goal-directed therapy in bleeding trauma patients with TIC.

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2.80
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10.50%
发文量
59
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