Rabeea F Omar, Maurice Boissinot, Ann Huletsky, Michel G Bergeron
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引用次数: 0
摘要
传染病(IDs)是导致死亡的主要原因。微生物的多样性和适应性对健康构成了持续的威胁。我们的跨学科医学研究团队将远见与激情相结合,在过去的五十年里,通过医学发现和创新,将工作重点放在更好地控制传染病上,以挽救人类的生命。该团队采用多方面的综合方法,通过基础发现、开发创新型预防工具和快速分子诊断检测来控制传染病,以满足患者和卫生专业人员在 ID 领域尚未得到满足的各种需求。在本文中,作为目标,我们将介绍 ID 管理的两个主要研究领域:由妇女控制的创新型感染预防,以及感染和耐药性的快速分子诊断。我们还解释了从生物学到工程学等不同领域的专家如何通过跨学科方法取得成功。此外,我们还讨论了我们对未来转化研究的愿景,以更好地应对 ID。
Tackling Infectious Diseases with Rapid Molecular Diagnosis and Innovative Prevention.
Infectious diseases (IDs) are a leading cause of death. The diversity and adaptability of microbes represent a continuing risk to health. Combining vision with passion, our transdisciplinary medical research team has been focussing its work on the better management of infectious diseases for saving human lives over the past five decades through medical discoveries and innovations that helped change the practice of medicine. The team used a multiple-faceted and integrated approach to control infectious diseases through fundamental discoveries and by developing innovative prevention tools and rapid molecular diagnostic tests to fulfill the various unmet needs of patients and health professionals in the field of ID. In this article, as objectives, we put in context two main research areas of ID management: innovative infection prevention that is woman-controlled, and the rapid molecular diagnosis of infection and resistance. We also explain how our transdisciplinary approach encompassing specialists from diverse fields ranging from biology to engineering was instrumental in achieving success. Furthermore, we discuss our vision of the future for translational research to better tackle IDs.