孕妇接种疫苗可预防婴儿患呼吸道合胞病毒支气管炎

Carlos Ochoa, Enrique Rodríguez-Salinas
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引用次数: 0

摘要

作者的结论:孕妇在妊娠最后三个月接种预防呼吸道合胞病毒的 F 蛋白预融合疫苗,可预防婴儿感染该病毒的严重呼吸道感染,且不会产生重要的不良反应。评论者的评论:该疫苗似乎有效且安全,尽管其疗效估计并不精确。它是在新生儿中使用尼舍单抗的替代性预防方案,预期效果相当。
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Vaccinating pregnant women can prevent respiratory syncytial virus bronchiolitis in infants
Authors´ conclusions: prefusion F protein vaccine against respiratory syncytial virus administered to pregnant women in the last trimester of pregnancy prevents this virus severe respiratory infections in their infants, without important adverse effects. Reviewers´ commentary: The vaccine appears effective and safe, although its efficacy estimates are imprecise. It constitutes an alternative preventive option to the administration of nirsevimab in the newborn, with comparable impact expectations.
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