泪膜质量对视觉功能的影响

Q2 Medicine Vision (Switzerland) Pub Date : 2024-02-26 DOI:10.3390/vision8010008
Snježana Kaštelan, Ksenija Gabrić, Maša Mikuličić, Danijela Mrazovac Zimak, Mirela Karabatić, Antonela Gverović Antunica
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引用次数: 0

摘要

背景:干眼症(DED)的发病率在全球范围内呈上升趋势,导致各种以不适和视力障碍为特征的眼部症状。对该疾病的准确诊断往往具有挑战性和复杂性,需要专门的诊断工具。本研究旨在调查泪膜不稳定性对视觉功能的影响,并评估眨眼后模糊时间(PBBT)作为评估泪膜稳定性的替代方法的价值:研究包括 62 名受试者:方法:研究包括 62 名受试者:31 名有 DED 主观症状的受试者(A 组)和由 31 名健康受试者组成的对照组(B 组)。采用标准的 Schein 问卷评估症状,并补充了其他问题。使用标准斯奈伦图表测量 PBBT,以研究 PBBT 与泪膜功能障碍之间的潜在联系。其他临床评估包括泪膜破裂时间(TBUT):受检组之间的 PBBT 和 TBUT 平均值存在明显统计学差异。DED 组的平均 PBBT 为 8.95 ± 5.38 秒,对照组为 14.66 ± 10.50 秒,P < 0.001。A 组的平均 TBUT 为 4.77 ± 2.37 秒,B 组为 7.63 ± 3.25 秒,P < 0.001。此外,PBBT 值与 TBUT 值之间存在很强的正相关性(r = 0.455;p < 0.001):研究证实,泪膜稳定性在光线折射和维持视力光学质量方面起着重要作用。PBBT 有可能成为一种客观且具有临床意义的 DED 筛选测试。
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The Influence of Tear Film Quality on Visual Function.

Background: The prevalence of dry eye disease (DED) is increasing globally, resulting in a variety of eye symptoms characterized by discomfort and visual disturbances. The accurate diagnosis of the disease is often challenging and complex, requiring specialized diagnostic tools. This study aimed to investigate the impact of tear film instability on visual function and to evaluate the value of post-blink blur time (PBBT) as an alternative method for assessing tear film stability.

Methods: The study included 62 subjects: 31 with subjective symptoms of DED (Group A) and a control group consisting of 31 healthy participants (Group B). Symptoms were assessed using the standard Schein questionnaire, supplemented with additional questions. PBBT was measured using standard Snellen charts to investigate a potential association between PBBT and tear film dysfunction. Additional clinical assessments included tear film break-up time (TBUT).

Results: Statistically significant differences were observed in the average values of PBBT and TBUT between the examined groups. The average PBBT was 8.95 ± 5.38 s in the group with DED and 14.66 ± 10.50 s in the control group, p < 0.001. Group A exhibited an average TBUT of 4.77 ± 2.37 s, while Group B had a TBUT of 7.63 ± 3.25 s, p < 0.001. Additionally, a strong positive correlation was identified between PBBT and TBUT values (r = 0.455; p < 0.001).

Conclusions: The research confirms that tear film stability has an important role in the refraction of light and the maintenance of optical quality of vision. PBBT could potentially function as an objective and clinically significant screening test for DED.

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来源期刊
Vision (Switzerland)
Vision (Switzerland) Health Professions-Optometry
CiteScore
2.30
自引率
0.00%
发文量
62
审稿时长
11 weeks
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