Jourdan E. Lakes , Jessica L. Ferrell , Mark A. Berhow , Michael D. Flythe
{"title":"大麻二酚对某些重要农业梭菌的抗菌作用。","authors":"Jourdan E. Lakes , Jessica L. Ferrell , Mark A. Berhow , Michael D. Flythe","doi":"10.1016/j.anaerobe.2024.102843","DOIUrl":null,"url":null,"abstract":"<div><p>Amino acid-fermenting Clostridia have undesirable effects in agricultural systems, which can be mitigated by antibiotics, but resistance necessitates alternatives. Here, we demonstrate the efficacy of cannabidiol on growth and ammonia inhibition of five agriculturally relevant Clostridia: <em>Clostridium sporogenes</em>, <em>Peptostreptococcus</em> spp., <em>Clostridioides difficile</em>, <em>Acetoanaerobium sticklandii</em>, and <em>Clostridium aminophilum</em>.</p></div>","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S107599642400026X/pdfft?md5=c4ef856ff01518283ff4498b29dbb0ba&pid=1-s2.0-S107599642400026X-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Antimicrobial effects of cannabidiol on select agriculturally important Clostridia\",\"authors\":\"Jourdan E. Lakes , Jessica L. Ferrell , Mark A. Berhow , Michael D. Flythe\",\"doi\":\"10.1016/j.anaerobe.2024.102843\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Amino acid-fermenting Clostridia have undesirable effects in agricultural systems, which can be mitigated by antibiotics, but resistance necessitates alternatives. Here, we demonstrate the efficacy of cannabidiol on growth and ammonia inhibition of five agriculturally relevant Clostridia: <em>Clostridium sporogenes</em>, <em>Peptostreptococcus</em> spp., <em>Clostridioides difficile</em>, <em>Acetoanaerobium sticklandii</em>, and <em>Clostridium aminophilum</em>.</p></div>\",\"PeriodicalId\":2,\"journal\":{\"name\":\"ACS Applied Bio Materials\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2024-03-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S107599642400026X/pdfft?md5=c4ef856ff01518283ff4498b29dbb0ba&pid=1-s2.0-S107599642400026X-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Applied Bio Materials\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S107599642400026X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, BIOMATERIALS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S107599642400026X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
Antimicrobial effects of cannabidiol on select agriculturally important Clostridia
Amino acid-fermenting Clostridia have undesirable effects in agricultural systems, which can be mitigated by antibiotics, but resistance necessitates alternatives. Here, we demonstrate the efficacy of cannabidiol on growth and ammonia inhibition of five agriculturally relevant Clostridia: Clostridium sporogenes, Peptostreptococcus spp., Clostridioides difficile, Acetoanaerobium sticklandii, and Clostridium aminophilum.