一例 5 岁儿童因急性肠道感染并发小肠结肠炎而导致的溶血性尿毒症综合征病例

O. V. Molochkova, S. B. Orekhova, R. V. Ovechkin, V. S. Vyshlova, V. V. Glukhova, O. Kovalev, N. Y. Egorova, A. Chashchukhina, V. A. Masyakin, E. P. Egorova, A. A. Sakharova, A. G. Okhtyarkina
{"title":"一例 5 岁儿童因急性肠道感染并发小肠结肠炎而导致的溶血性尿毒症综合征病例","authors":"O. V. Molochkova, S. B. Orekhova, R. V. Ovechkin, V. S. Vyshlova, V. V. Glukhova, O. Kovalev, N. Y. Egorova, A. Chashchukhina, V. A. Masyakin, E. P. Egorova, A. A. Sakharova, A. G. Okhtyarkina","doi":"10.22627/2072-8107-2024-23-1-62-67","DOIUrl":null,"url":null,"abstract":"Purpose: to demonstrate a case of hemolytic-uremic syndrome (HUS) in a 5-year-old child associated with an acute intestinal infection of unknown etiology, occurring with hemocolitis. Results. During clinical and laboratory observation, edematous syndrome, oligoanuria, severe microangiopathic hemolytic anemia (decrease in hemoglobin, haptoglobin, increase in Lactate dehydrogenase), thrombocytopenia, consumption coagulopathy, hyperazotemia, acute kidney injury (AKI) according to KDIGO grade 2 (increase in serum creatinine more than 2 times) developed. As part of complex therapy with balanced crystalloid solutions with stimulation of diuresis, it was possible to achieve rapid restoration of diuresis on the 2nd day of hospital stay without the use of renal replacement therapy; he also received antibiotics, anticoagulants, transfusion of fresh frozen plasma and red blood cell suspension. Hyperazotemia was relieved within 5 days, as was thrombocytopenia. The follow-up recovery of renal function showed.","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A case of hemolytic-uremic syndrome that developed in a 5-year-old child due to acute intestinal infection with hemocolitis\",\"authors\":\"O. V. Molochkova, S. B. Orekhova, R. V. Ovechkin, V. S. Vyshlova, V. V. Glukhova, O. Kovalev, N. Y. Egorova, A. Chashchukhina, V. A. Masyakin, E. P. Egorova, A. A. Sakharova, A. G. Okhtyarkina\",\"doi\":\"10.22627/2072-8107-2024-23-1-62-67\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Purpose: to demonstrate a case of hemolytic-uremic syndrome (HUS) in a 5-year-old child associated with an acute intestinal infection of unknown etiology, occurring with hemocolitis. Results. During clinical and laboratory observation, edematous syndrome, oligoanuria, severe microangiopathic hemolytic anemia (decrease in hemoglobin, haptoglobin, increase in Lactate dehydrogenase), thrombocytopenia, consumption coagulopathy, hyperazotemia, acute kidney injury (AKI) according to KDIGO grade 2 (increase in serum creatinine more than 2 times) developed. As part of complex therapy with balanced crystalloid solutions with stimulation of diuresis, it was possible to achieve rapid restoration of diuresis on the 2nd day of hospital stay without the use of renal replacement therapy; he also received antibiotics, anticoagulants, transfusion of fresh frozen plasma and red blood cell suspension. Hyperazotemia was relieved within 5 days, as was thrombocytopenia. The follow-up recovery of renal function showed.\",\"PeriodicalId\":9855,\"journal\":{\"name\":\"CHILDREN INFECTIONS\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-03-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"CHILDREN INFECTIONS\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22627/2072-8107-2024-23-1-62-67\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"CHILDREN INFECTIONS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22627/2072-8107-2024-23-1-62-67","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

目的:展示一例 5 岁儿童溶血性尿毒症(HUS)病例,该病例与病因不明的急性肠道感染有关,并伴有小儿结肠炎。结果。在临床和实验室观察期间,患儿出现了水肿综合征、少尿症、严重的微血管病性溶血性贫血(血红蛋白、血红蛋白下降,乳酸脱氢酶升高)、血小板减少症、消耗性凝血病、高氮血症、KDIGO 2级急性肾损伤(血清肌酐升高2倍以上)。作为使用平衡晶体液刺激利尿的复合疗法的一部分,他在住院第 2 天就迅速恢复了利尿功能,而无需使用肾脏替代疗法;他还接受了抗生素、抗凝剂、新鲜冰冻血浆和红细胞悬液的输注。高氮血症和血小板减少症在 5 天内得到缓解。后续的肾功能恢复情况显示:
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
A case of hemolytic-uremic syndrome that developed in a 5-year-old child due to acute intestinal infection with hemocolitis
Purpose: to demonstrate a case of hemolytic-uremic syndrome (HUS) in a 5-year-old child associated with an acute intestinal infection of unknown etiology, occurring with hemocolitis. Results. During clinical and laboratory observation, edematous syndrome, oligoanuria, severe microangiopathic hemolytic anemia (decrease in hemoglobin, haptoglobin, increase in Lactate dehydrogenase), thrombocytopenia, consumption coagulopathy, hyperazotemia, acute kidney injury (AKI) according to KDIGO grade 2 (increase in serum creatinine more than 2 times) developed. As part of complex therapy with balanced crystalloid solutions with stimulation of diuresis, it was possible to achieve rapid restoration of diuresis on the 2nd day of hospital stay without the use of renal replacement therapy; he also received antibiotics, anticoagulants, transfusion of fresh frozen plasma and red blood cell suspension. Hyperazotemia was relieved within 5 days, as was thrombocytopenia. The follow-up recovery of renal function showed.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
A case of hemolytic-uremic syndrome that developed in a 5-year-old child due to acute intestinal infection with hemocolitis Severe forms of hereditary spherocytosis in children with congenital active cytomegalovirus infection Parasitic infestations in children in a metropolis Sparganosis Non-immune hydrops fetalis: etiology, pathogenesis, features of diagnosis and treatment in the fetus and newborn
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1