眼部弓形虫引起的非典型单侧视神经病变

Jong Min Lee, In Kwon Chung, Hun Jin Choi
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摘要

目的:报告一种表现为单侧视神经病变的非典型眼部弓形虫病。病例摘要:一名 75 岁的男性因右眼最近出现视力障碍而被转诊至我院。右眼视力为 0.4,右眼瞳孔相对传入缺损呈阳性。裂隙灯生物显微镜检查发现,右眼前房发炎,玻璃体细胞和混浊。眼底检查发现,右眼视盘肿胀,视盘周围有局灶性视网膜炎。荧光素血管造影显示右眼视盘附近有局灶性视网膜炎和渗漏。血清学检查结果为弓形虫 IgG 阳性。由于怀疑是非典型的眼部弓形虫病,患者接受了局部和口服类固醇及阿苯达唑治疗。随后,视盘肿胀和玻璃体炎症有所改善,但最终视力为 0.125,右眼视盘苍白,中心视野缺损:在疑似视神经炎的患者中,当前房和玻璃体炎症以及葡萄膜炎同时存在时,眼弓形虫病可能会出现异常表现,需要引起注意,因为可能会造成不可逆的视神经损伤,预后不良。
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Atypical Form of Unilateral Optic Neuropathy Caused by Ocular Toxocariasis
Purpose: To report an atypical form of ocular toxocariasis presenting as unilateral optic neuropathy.Case summary: A 75-year-old man was referred to our clinic owing to the recently developed visual difficulty in his right eye. The visual acuity of the right eye was 0.4, a relative afferent pupillary defect was positive in the right eye. On slit lamp biomicroscopy, anterior chamber inflammation and vitreous cells and haze were detected in the right eye. On fundus examination, optic disc swelling and focal retinitis around the optic disc were found in the right eye. Fluorescein angiography revealed focal retinitis along with leakage near the optic disc in the right eye. Serology was positive for Toxocara IgG. Under the suspicion of an atypical form of ocular toxocariasis, the patient was treated with local and oral steroids and albendazole. Subsequently, optic disc swelling and vitreous inflammation improved, but the final visual acuity was 0.125 with pale optic disc and central visual field defects in the right eye.Conclusions: In patients suspected of optic neuritis, when the anterior chamber and vitreous inflammation and uveitis are accompanied, ocular toxocariasis can present atypically and requires attention because may have a bad prognosis owing to irreversible optic nerve damage.
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