{"title":"摘要 1960 hERG 通道的 N 端 Per-Arnt-Sim (PAS) 结构域对通道关闭进行异构调节,并将电压传感器与孔门耦合在一起。","authors":"Sara J. Codding, Matt Trudeau","doi":"10.1016/j.jbc.2024.107015","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":51075,"journal":{"name":"Journal of Biological Chemistry","volume":"17 8","pages":""},"PeriodicalIF":4.8000,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Abstract 1960 The N-terminal Per-Arnt-Sim (PAS) domain of hERG channels allosterically regulates channel closure and couples the voltage sensor to the pore gate\",\"authors\":\"Sara J. Codding, Matt Trudeau\",\"doi\":\"10.1016/j.jbc.2024.107015\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":51075,\"journal\":{\"name\":\"Journal of Biological Chemistry\",\"volume\":\"17 8\",\"pages\":\"\"},\"PeriodicalIF\":4.8000,\"publicationDate\":\"2024-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Biological Chemistry\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1016/j.jbc.2024.107015\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Biochemistry, Genetics and Molecular Biology\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biological Chemistry","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.jbc.2024.107015","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
Abstract 1960 The N-terminal Per-Arnt-Sim (PAS) domain of hERG channels allosterically regulates channel closure and couples the voltage sensor to the pore gate
期刊介绍:
The Journal of Biological Chemistry welcomes high-quality science that seeks to elucidate the molecular and cellular basis of biological processes. Papers published in JBC can therefore fall under the umbrellas of not only biological chemistry, chemical biology, or biochemistry, but also allied disciplines such as biophysics, systems biology, RNA biology, immunology, microbiology, neurobiology, epigenetics, computational biology, ’omics, and many more. The outcome of our focus on papers that contribute novel and important mechanistic insights, rather than on a particular topic area, is that JBC is truly a melting pot for scientists across disciplines. In addition, JBC welcomes papers that describe methods that will help scientists push their biochemical inquiries forward and resources that will be of use to the research community.