NSCLC全身免疫炎症指数的预后意义：一项荟萃分析

Pub Date : 2024-02-28 DOI:10.2217/lmt-2023-0010

Wen-Hua Chen, Jing-Jing Shao, Ying Yang, Yun Meng, Sheng Huang, Rong-Fang Xu, Ji-Bin Liu, Jian-Guo Chen, Qin Wang, Hai-Zhen Chen

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引用次数: 0

摘要

目的：本荟萃分析旨在研究基线全身免疫炎症指数（SII）与 NSCLC 患者预后之间的关系。材料与方法：分析治疗前 SII 与 NSCLC 患者总生存期、无病生存期、癌症特异性生存期、无进展生存期和无复发生存期之间的关系，并结合危险比和 95% CI。结果显示结果显示，高 SII 与 NSCLC 患者的总生存期和无进展生存期显著相关，但与无病生存期、癌症特异性生存期和无复发生存期无关。结论研究表明，SII越高，NSCLC患者的预后越差。PROSPERO 注册号CRD42022336270 .

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Prognostic significance of systemic immune inflammatory index in NSCLC: a meta-analysis

Aim: The aim of this meta-analysis was to investigate the relationship between the baseline systemic immune inflammatory index (SII) and prognosis in patients with NSCLC. Materials & methods: The relation between pretreatment SII and overall survival, disease-free survival, cancer-specific survival, progression-free survival and recurrence-free survival in NSCLC patients was analyzed combined with hazard ratio and 95% CI. Results: The results showed that high SII was significantly correlated with overall survival and progression-free survival of NSCLC patients, but not with disease-free survival, cancer-specific survival and recurrence-free survival. Conclusion: The study suggests that a higher SII has association with worse prognosis in NSCLC patients. PROSPERO registration number: CRD42022336270 .

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