荟萃分析是心脏病学证据金字塔的 "塔尖 "吗？

Q3 Social Sciences Cardiovascular Therapy and Prevention Pub Date : 2024-02-24 DOI:10.15829/1728-8800-2024-3925

S. Martsevich

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引用次数: 0

摘要

作者评论了荟萃分析在现代循证医学（主要是心脏病学）中的意义和地位。简要介绍了荟萃分析的历史。回顾了荟萃分析的主要局限性。举例说明对同一问题进行的荟萃分析得出了截然相反的结果。讨论了荟萃分析在确定药物副作用方面的重要性。证明了操纵元分析结果的可能性。作者的结论是，元分析应被排除在一级证据之外，在证据等级中的作用应更加适中。

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Is meta-analysis the "top of the evidence pyramid" in cardiology?

The author comments on the significance and place of meta-analyses in modern evidence-based medicine, primarily in cardiology. The history of meta-analyses is briefly described. The main limitations of meta-analyses are reviewed. Examples are given where meta-analyses on the same problem had directly opposite results. The importance of meta-analyses in identifying side effects of drugs is discussed. The possibility of manipulating the results of meta-analyses is demonstrated. The significance of meta-analyses is currently being assessed through the example of the coronavirus pandemic, when different meta-analyses assessed the effectiveness and safety of the same drugs differently.The author concludes that meta-analyses should be excluded from level I evidence and given a more modest role in the hierarchy of evidence.

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来源期刊

Cardiovascular Therapy and Prevention Medicine-Cardiology and Cardiovascular Medicine

CiteScore

1.70

自引率

0.00%

发文量

155

审稿时长

6-12 weeks

期刊介绍： The most important objectives of the journal are: the generalization of scientific and practical achievements in the field of cardiology, increasing scientific and practical skills of cardiologists. The scientific concept of publication does the publication of modern achievements in the field of epidemiology, prevention and treatment of cardiovascular diseases, the results of research, national and international clinical trials. For publication in the journal are invited both domestic and foreign scientists and clinicians working in the field of cardiology, as well as doctors of other specialties. The magazine covers various issues in cardiology and related specialties. Each issue is prepared by Executive editor of the issue, a respected specialist in the field of epidemiology, prevention and treatment of cardiovascular diseases. The main focus of the publication — scientific articles on original research, the pharmacotherapy of cardiovascular disease, new diagnostic methods. All members of the group of authors should meet all four criteria of authorship set forth in the ICMJE recommendations: 1) concept and design development or data analysis and interpretation, and 2) manuscript justification or verification of critical intellectual content, and 3) final approval for publication of the manuscript, and 4) consent to be responsible for all aspects of the work, and assume that issues relating to the thoroughness and diligent execution of any part of the study submitted are duly investigated and resolved. Great importance the editors attached to the preparation of scientific papers by groups of authors at a high level, literacy, authors, and their ownership information, availability of research results not only to colleagues in Russia, but also abroad.