癌症治疗中的免疫疗法:利用免疫系统的力量

Alok Kumar, Kanchan Singh, Kartik Kumar, Sachin Kumar, Arjun Singh, Alpesh Tripath, Lakshya Tiwari
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引用次数: 0

摘要

免疫疗法利用人体的免疫系统对抗癌细胞,为癌症治疗带来了革命性的变化。本文概述了免疫疗法,重点介绍了免疫疗法的不同模式、作用机制、临床应用以及免疫相关不良反应的处理。免疫检查点抑制剂,如 PD-1 和 CTLA-4 抑制剂,是通过阻断调节蛋白来增强免疫反应的主要模式。此外,CAR-T疗法对患者的T细胞进行基因改造,使其针对癌细胞上的特定蛋白,从而精确地消灭癌细胞。免疫疗法在某些恶性肿瘤中取得了显著的成功,为癌症患者带来了新的希望。
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Immunotherapy in Cancer Treatment: Harnessing the Power of the Immune System
Immunotherapy has revolutionized cancer treatment by leveraging the body's immune system to fight against cancer cells. This article provides an overview of immunotherapy, focusing on its different modalities, mechanisms of action, clinical applications, and the management of immune-related adverse events. Immune checkpoint inhibitors, such as PD-1 and CTLA-4 inhibitors, are prominent modalities that enhance the immune response by blocking regulatory proteins. Additionally, CAR-T therapy genetically modifies a patient's T cells to target specific proteins on cancer cells, leading to precise cancer cell elimination. Immunotherapy has demonstrated remarkable success in certain malignancies and offers new hope for patients battling cancer.
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