接受冠状动脉旁路移植术患者的动脉粥样硬化风险因素与颈动脉狭窄之间的关系

Mohammad Saleh Sadeghi, Leili Iranirad, Negar Vakili Razlighi, Fatemeh Lotfi, Hadi Vakili Razlighi, Mohammad Miri
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摘要

背景:对动脉粥样硬化的危险因素和颈动脉狭窄的评估已进行过多次调查。本研究旨在确定冠状动脉旁路移植术(CABG)患者的颈动脉狭窄程度,并调查动脉粥样硬化风险因素与冠状动脉受累之间的关系:这项横断面研究的对象是在库姆沙希德-贝赫什提医院就诊的 450 名 CABG 候选患者。根据颈动脉狭窄程度将患者分为 4 组,并对动脉粥样硬化和冠状动脉受累的危险因素进行了检查。最后,使用 SPSS 统计软件对数据进行了分析:共有约 18% 的患者有颈动脉狭窄,其中 13.6% 的狭窄程度小于 50%,3.2% 的狭窄程度为 50%-70%,1.2% 的狭窄程度大于 70%。年龄、高血压(HTN)病史、高脂血症和脑血管意外(CVA)病史与颈动脉狭窄有显著关系。但是,患者的性别、体重指数、糖尿病、吸烟史、血管造影史和血脂状况与颈动脉狭窄无明显关系。此外,CABG 术后 CVA 的发生率为 1.2%:本研究表明,高龄、高血压、高脂血症和 CVA 病史与颈动脉狭窄的严重程度直接相关。
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Relationship between Atherosclerosis Risk Factors and Carotid Artery Stenosis in Patients Undergoing Coronary Artery Bypass Graft
Background: Evaluation of the risk factors of atherosclerosis and carotid artery stenosis have been subjected to several investigations. The present study was conducted to determine the degree of carotid artery stenosis and investigate the relationship between atherosclerosis risk factors and coronary artery involvement in coronary artery bypass graft (CABG) patients. Methods: This cross-sectional study was conducted on 450 CABG candidate patients who visited Shahid Beheshti Hospital in Qom. The patients were divided into 4 groups according to the degree of carotid artery stenosis and were examined in terms of risk factors for atherosclerosis and coronary artery involvement. Finally, the data were analyzed using SPSS statistical software. Results: In total, about 18% of the patients had carotid artery stenosis, of them 13.6% had stenosis of less than 50%, 3.2% had stenosis of 50%–70%, and 1.2% had stenosis of more than 70%. Age, history of hypertension (HTN), hyperlipidemia, and previous history of cerebrovascular accident (CVA) showed a significant relationship with carotid artery stenosis. However, gender, BMI, diabetes, history of smoking, history of angiography and lipid profile of the patients did not show a significant relationship. Also, the incidence of CVA after CABG was 1.2%. Conclusion: The present study showed that old age, HTN, hyperlipidemia, and history of CVA are directly related to the severity of carotid artery stenosis.
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